Periodontal lesions in hamsters and gnotobiotic rats infected with actinomyces of human origin.
Periodontal lesions in hamsters and gnotobiotic rats infected with actinomyces of human origin.
复制标题
感染人类放线菌的仓鼠和无菌大鼠的牙周病变。
DOI：
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发表时间：
1972
影响因子：
3.5
通讯作者：
S. Bellack
中科院分区：
文献类型：
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作者：
H. Jordan;P. Keyes;S. Bellack
感染了一种人类来源的过氧化氢酶阴性放线菌的白化仓鼠出现了与先前在仓鼠中描述的相似的牙根表面和牙周综合症。牙根斑块沉积形成，牙槽骨吸收区域邻近被大量斑块覆盖的牙齿表面。牙菌斑中含有大量与感染菌株具有相同特征的微生物。
两组灵知生菌大鼠分别感染了两株人放线菌，其中一株代表粘性放线菌。牙龈变形、牙槽凹陷、牙槽骨裂和根面龋病与毛发纤维的嵌塞和根面细菌垫的形成有关。在许多地区，上颌第一磨牙和第二磨牙暴露的牙根表面有超过一半的细菌覆盖。乳牙本质和次级牙本质经常被这些微生物的入侵破坏，在某些情况下，这些微生物穿透到牙髓室。
Albino hamsters infected with a catalase negative strain of Actinomyces of human origin developed a root surface and periodontal syndrome similar to that previously described in hamsters. Deposits of radicular plaque developed, and areas of alveolar bone resorption were noted adjacent to tooth surfaces that had been coated with copious amounts of plaque. Gingival plaque contained large numbers of microorganisms with identical characteristics to those of the infecting strain.
Groups of gnotobiotic rats were separately infected with two human strains of Actinomyees, one of which was representative of A. viscosus. Gingival distortion, pocketing, alveoloclasia, and root caries were associated with the impaction of hair fibers and the formation of bacterial mats on root surfaces. In many areas bacterial coats had spread over more than half of the exposed root surfaces of maxillary first and second molars. Primary and secondary dentin was often destroyed by an invasion of these microorganisms that in some cases penetrated to the pulp chamber.