Parasympathetic vasodilatorfibers in rat digastric muscle
Parasympathetic vasodilatorfibers in rat digastric muscle
复制标题
大鼠二腹肌的副交感血管舒张纤维
DOI：
10.1016/j.brainres.2009.09.035
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发表时间：
2009
期刊：
影响因子：
2.9
通讯作者：
Hirai T and Izumi H.
中科院分区：
文献类型：
--
作者：
Sudo E;Ishii H;Niioka T;Hirai T and Izumi H.
本研究探讨是否存在副交感神经血管扩张纤维在大鼠下颌张开肌肉，如二腹肌。刺激颏神经以激活二腹肌中的副交感血管扩张神经。电刺激精神神经引起强度和频率依赖性增加血流量在这方面的肌肉。这些增加显着减少六甲铵的剂量和时间依赖性的方式，但预处理酚妥拉明或普萘洛尔没有影响。阿托品预处理也减弱了二腹肌血流量的增加。当逆行荧光金注入二腹肌，标记的神经元只在同侧的耳神经节观察到，但没有在翼腭神经节的任何一方。这些结果表明，副交感神经血管扩张纤维起源于细胞体的耳神经节在大鼠二腹肌。
The present study examined whether parasympathetic vasodilator fibers exist in rat jaw-opening muscles such as the digastric muscle. The mental nerve was stimulated to activate the parasympathetic vasodilator nerve in the digastric muscle. Electrical stimulation of the mental nerve elicited intensity- and frequency-dependent increases of blood flow in this muscle. These increases were markedly reduced by hexamethonium in dose- and time-dependent manners, but pretreatment with phentolamine or propranolol had no effect. Pretreatment with atropine also attenuated the increase in blood flow in digastric muscle. When retrograde fluorogold was injected into the digastric muscle, labeled neurons were observed in the otic ganglion only on the ipsilateral side, but not in the pterygopalatine ganglion of either side. These results indicate that parasympathetic vasodilator fibers originate from cell bodies in the otic ganglion in rat digastric muscle.