High-Sensitivity Cardiac Troponin T and Risk of Hypertension
High-Sensitivity Cardiac Troponin T and Risk of Hypertension
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DOI：
10.1161/circulationaha.114.014364
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发表时间：
2015-09-01
期刊：
影响因子：
37.8
通讯作者：
Selvin, Elizabeth
中科院分区：
文献类型：
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作者：
McEvoy, John W.;Chen, Yuan;Selvin, Elizabeth
背景高血压的诊断通常以心脏结构异常为前提。因此，我们评估了高敏感性心肌肌钙蛋白T (hs-cTnT)，亚临床心肌损伤的标志，是否可以识别有高血压或左心室肥厚风险的个体。方法和结果我们研究了6516名社区动脉粥样硬化风险（ARIC）研究参与者，他们在基线时没有高血压和心血管疾病。我们检查了基线hs-cTnT类别与事件诊断高血压（由自我报告诊断或最长19.9年随访期间的药物使用来定义）和事件就诊高血压（由自我报告、药物使用或6年内测量血压bb0 140/90 mmHg来定义）的关联。相对于hs-cTnT
Background The diagnosis of hypertension is often preceded by cardiac structural abnormalities. Thus, we assessed whether high-sensitivity cardiac troponin T (hs-cTnT), a marker of subclinical myocardial damage, can identify individuals at risk for hypertension or left ventricular hypertrophy.Methods and Results We studied 6516 Atherosclerosis Risk in Communities (ARIC) Study participants who were free of prevalent hypertension and cardiovascular disease at baseline (1990-1992). We examined the association of baseline hs-cTnT categories with incident diagnosed hypertension (defined by self-report of a diagnosis or medication use during a maximum of 19.9 years of follow-up) and with incident visit-based hypertension (defined by self-report, medication use, or measured blood pressure >140/90 mmHg over 6 years). Relative to hs-cTnT