Information Processing in the Primate Basal Ganglia during Sensory-Guided and Internally Driven Rhythmic Tapping
Information Processing in the Primate Basal Ganglia during Sensory-Guided and Internally Driven Rhythmic Tapping
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DOI：
10.1523/jneurosci.2679-13.2014
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发表时间：
2014-03-12
影响因子：
5.3
通讯作者：
Merchant, Hugo
中科院分区：
文献类型：
--
作者：
Bartolo, Ramon;Prado, Luis;Merchant, Hugo
Gamma (gamma) and beta (beta) oscillations seem to play complementary functions in the cortico-basal ganglia-thalamo-cortical circuit (CBGT) during motor behavior. We investigated the time-varying changes of the putaminal spiking activity and the spectral power of local field potentials (LFPs) during a task where the rhythmic tapping of monkeys was guided by isochronous stimuli separated by a fixed duration (synchronization phase), followed by a period of internally timed movements (continuation phase). We found that the power of both bands and the discharge rate of cells showed an orderly change in magnitude as a function of the duration and/or the serial order of the intervals executed rhythmically. More LFPs were tuned to duration and/or serial order in the beta-than the gamma-band, although different values of preferred features were represented by single cells and by both bands. Importantly, in the LFPs tuned to serial order, there was a strong bias toward the continuation phase for the beta-band when aligned to movements, and a bias toward the synchronization phase for the gamma-band when aligned to the stimuli. Our results suggest that gamma-oscillations reflect local computations associated with stimulus processing, whereas beta-activity involves the entrainment of large putaminal circuits, probably in conjunction with other elements of CBGT, during internally driven rhythmic tapping.
