Single-scan longitudinal relaxation measurements in high-resolution NMR spectroscopy
Single-scan longitudinal relaxation measurements in high-resolution NMR spectroscopy
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DOI：
10.1016/s1090-7807(03)00186-1
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发表时间：
2003-10-01
影响因子：
2.2
通讯作者：
Griffin, RG
中科院分区：
文献类型：
--
作者：
Loening, NM;Thrippleton, MJ;Griffin, RG
提出了几种测量纵向弛豫时间(T-1)的单扫描实验。这些实验可以快速而准确地确定弛豫速率，对脉冲缺陷相对稳定，并保存有关化学位移的信息。这些实验中使用的方法是首先将T-1值编码为磁化强度的空间变化，然后通过在采集期间施加弱梯度或通过顺序观察样品的不同切片来读出该变化。结果，可以将确定T-1值所需的时间减少一个或两个数量级。这种节省时间的代价是以产生的光谱的信噪比水平和一些化学位移分辨率为代价的。(C)2003年埃尔塞维尔科学公司(美国)。版权所有。
Several single-scan experiments for the measurement of the longitudinal relaxation time (T-1) are proposed. These experiments result in fast and accurate determinations of the relaxation rate, are relatively robust to pulse imperfections, and preserve information about the chemical shift. The method used in these experiments is to first encode the T-1 values as a spatial variation of the magnetization and then to read out this variation either by applying a weak gradient during acquisition or by sequentially observing different slices of the sample. As a result, it is possible to reduce the time necessary to determine the T-1 values by one or two orders of magnitude. This time saving comes at the expense of the signal-to-noise level of the resulting spectrum and some chemical shift resolution. (C) 2003 Elsevier Science (USA). All rights reserved.