Critical cerebral blood flow for production of hemiparesis after unilateral carotid occlusion in the gerbil.
Critical cerebral blood flow for production of hemiparesis after unilateral carotid occlusion in the gerbil.
复制标题
沙鼠单侧颈动脉闭塞后产生偏瘫的关键脑血流。
DOI：
10.1136/jnnp.40.6.595
复制
发表时间：
1977
期刊：
影响因子：
--
通讯作者：
J. Meyer
中科院分区：
文献类型：
--
作者：
K. Nakai;K. Welch;J. Meyer
本实验采用慢性植入氢电极的方法，对沙土鼠暂时性单侧颈总动脉（CCA）闭塞引起的短暂性脑缺血进行了研究。只有当同侧大脑半球的局部脑血流值低于0.20-0.22 ml/gm brain/min的临界范围时，单侧CCA闭塞才会产生神经功能缺损的行为体征。去除CCA闭塞后，缺血后灌注不良（无复流）是一种罕见的观察结果。
Transient cerebral ischaemia, produced by temporary unilateral common carotid artery (CCA) occlusion, was studied in the gerbil by means of chronically implanted hydrogen electrodes. Unilateral CCA occlusion produced behavioural signs of neurological deficit only when regional cerebral blood flow values in the ipsilateral cerebral hemisphere fell below a critical range of 0.20-0.22 ml/gm brain/min. Postischaemic poor perfusion (no-reflow) was an infrequent observation after removal of CCA occlusion.