Central nervous system lymphoma: magnetic resonance imaging features at presentation.

Central nervous system lymphoma: magnetic resonance imaging features at presentation.
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中枢神经系统淋巴瘤:磁共振成像特征。

DOI:
10.1590/s0004-282x2012000200005
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发表时间:
2012
影响因子:
1.4
通讯作者:
M. França
M. França
中科院分区:
医学4区
文献类型:
--
作者:
Ricardo Schwingel;F. Reis;V. Zanardi;L. S. Queiroz;M. França

文献摘要

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目的 本文旨在研究中枢神经系统(CNS)淋巴瘤的磁共振成像(MRI)所获得的结构图像的表现。 方法 通过频率和交叉表分析了1999年1月至2011年3月在一所大学医院诊断为CNS淋巴瘤的15例患者的MRI表现。 结果 所有患者都有幕上病变; 4例有幕下和幕上病变。T1和T2加权像信号主要是低或等信号。在T2加权像中,单个病灶与低信号成分相关。6例患者出现坏死,均显示病灶周围异常白色物质,9例累及脑膜,5例室管膜下扩散。室管膜下扩散和脑膜受累倾向于发生在年轻患者中。 结论 淋巴瘤的表现是非常多形性的,但其中一些应该指出这种诊断的可能性。
OBJECTIVE This paper aimed at studying presentations of the central nervous system (CNS) lymphoma using structural images obtained by magnetic resonance imaging (MRI). METHODS The MRI features at presentation of 15 patients diagnosed with CNS lymphoma in a university hospital, between January 1999 and March 2011, were analyzed by frequency and cross tabulation. RESULTS All patients had supratentorial lesions; and four had infra- and supratentorial lesions. The signal intensity on T1 and T2 weighted images was predominantly hypo- or isointense. In the T2 weighted images, single lesions were associated with a hypointense signal component. Six patients presented necrosis, all of them showed perilesional abnormal white matter, nine had meningeal involvement, and five had subependymal spread. Subependymal spread and meningeal involvement tended to occur in younger patients. CONCLUSION Presentations of lymphoma are very pleomorphic, but some of them should point to this diagnostic possibility.