Primary ciliary dyskinesia: age at diagnosis and symptom history
Primary ciliary dyskinesia: age at diagnosis and symptom history
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DOI：
10.1080/080352502760069089
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发表时间：
2002-01-01
期刊：
影响因子：
3.8
通讯作者：
Bush, A
中科院分区：
文献类型：
--
作者：
Coren, ME;Meeks, M;Bush, A
诊断年龄和症状的历史，儿童原发性睫状体运动障碍（PCD）是通过审查的情况下，在儿科PCD诊所。诊断时的平均年龄为4.4岁，尽管37/55例有新生儿呼吸窘迫病史。38155例中有38155例为异位性鼻炎，42/55例为早发性难治性鼻炎。重点介绍了不明原因新生儿呼吸困难、窘迫、早发性鼻炎、逆位和排痰性咳嗽的主要临床特征，特别是合并发生时。强制性规定早期转诊进行PCD特定检测。
Age at diagnosis and the Symptom history of children with primary ciliary dyskinesia (PCD) are described by reviewing the case notes in the paediatric PCD clinic. Mean age at diagnosis was 4.4 y despite a history of neonatal respirators distress in 37/55 cases. situs inversus in 38155 cases and early onset troublesome rhinitis in 42/55.Conclusion: Diagnosis of PCD is often delayed despite the presence of typical symptoms early in life. The key clinical features of unexplained neonatal respirator, distress, early onset rhinitis, situs inversus and a productive cough are highlighted, which, especially when occurring in combination. makes early referral for specific testing for PCD mandatory.