Salivary biomarkers in psychobiological medicine.
Salivary biomarkers in psychobiological medicine.
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DOI：
10.6026/97320630001331
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发表时间：
2006-12-29
期刊：
影响因子：
1.9
通讯作者：
Prolo P
中科院分区：
文献类型：
--
作者：
Chiappelli F;Iribarren FJ;Prolo P
唾液生物标记物用于诊断和预后评估的价值在医学、药理学和牙科中已越来越得到证实。某些唾液成分反映了生物体的神经内分泌状态。其他唾液产品本质上是蛋白质，可以用来反映免疫监测过程。自主神经系统调节唾液分泌的过程，以及其他唾液成分的浓度，如α-淀粉酶，这为交感反应提供了可靠的结果衡量标准。在这里，我们讨论分子技术，这些技术允许在利用唾液样本和微流体方面迈出巨大的一步，以造福于诊断医学和牙科，以及它们在推动心理生物学研究方面的假定作用。
The value of salivary biomarkers for diagnostic and prognostic assessments has become increasingly well established in medicine, pharmacology, and dentistry. Certain salivary components mirror the neuro-endocrine status of the organism. Other saliva products are protein in nature, and can serve to reflect immune surveillance processes. The autonomic nervous system regulates the process of salivation, and the concentration of yet other salivary components, such as α-amylase, which provide a reliable outcome measure of the sympathetic response. Here, we discuss molecular technologies that have permitted giant steps in the utilization of salivary samples and micro-fluidics for the benefit of diagnostic medicine and dentistry, and their putative role in springing forward research in psychobiology.