Impact of weight loss on Health-Related Quality of Life

Impact of weight loss on Health-Related Quality of Life
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DOI:
10.1023/a:1008835602894
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发表时间:
1999-05-01
影响因子:
3.5
通讯作者:
Franckowiak, SC
Franckowiak, SC
中科院分区:
医学2区
文献类型:
--
作者:
Fontaine, KR;Barofsky, I;Franckowiak, SC

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为了检验治疗引起的体重减轻对健康相关生活质量(HRQL)的影响,招募了38名轻度至中度超重的人参加一项研究,以检验生活方式改变治疗方案的疗效,他们完成了社会人口学问卷、贝克抑郁量表(BDI)、医学结局研究简表健康调查(SF-36,作为HRQL的评估),并在治疗前进行一系列临床评价。在基线评估后,参与者被随机分配到一个生活方式体育活动计划或传统的有氧活动计划。参与者在13周的治疗计划结束后再次完成SF-36和BDI。在为期13周的研究中,体重平均减轻8.6 +/- 2.8 kg。我们发现,体重减轻与SF-36的身体功能、身体角色、一般健康、活力和心理健康领域的评分(增强HRQL)相对于基线显著升高相关。最大的改善是在活力、一般健康观念和角色-身体领域。生活方式组和有氧运动组在任何研究指标上都没有显著差异。这些数据表明,至少在短期内,体重减轻似乎大大提高了HRQL。
To examine the effect of treatment-induced weight loss on Health-Related Quality of Life (HRQL), 38 mildly-to-moderately overweight persons recruited to participate in a study to examine the efficacy of a lifestyle modification treatment program completed a sociodemographic questionnaire, the Beck Depression Inventory (BDI), the Medical Outcomes Study Short-Form Health Survey (SF-36, as an assessment of HRQL), and underwent a series of clinical evaluations prior to treatment. After baseline evaluations, participants were randomly assigned to either a program of lifestyle physical activity or a program of traditional aerobic activity. Participants again completed the SF-36 and BDI after the 13-week treatment program had ended. Weight loss averaged 8.6 +/- 2.8 kg over the 13-week study. We found that weight loss was associated with significantly higher scores (enhanced HRQL), relative to baseline, on the physical functioning, role-physical, general health, vitality and mental health domains of the SF-36. The largest improvements were with respect to the vitality, general health perception and role-physical domains. There were no significant differences between the lifestyle and aerobic activity groups on any of the study measures. These data indicate that, at least in the short-term, weight loss appears to profoundly enhance HRQL.