Estimates of the prevalence of childhood seizure disorders in communities where professional resources are scarce: results from Bangladesh, Jamaica and Pakistan.
Estimates of the prevalence of childhood seizure disorders in communities where professional resources are scarce: results from Bangladesh, Jamaica and Pakistan.
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DOI：
10.1111/j.1365-3016.1992.tb00758.x
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发表时间：
1992-04-01
影响因子：
2.8
通讯作者：
Zaman, S
中科院分区：
文献类型：
--
作者：
Durkin, M S;Davidson, L L;Zaman, S
虽然目前已经发表了许多关于欠发达国家人群中癫痫发病率的估计，但由于缺乏研究方法和病例定义标准的可比性，这些估计很难解释。本文报告的结果来自一项针对2至9岁儿童残疾的大型合作研究，其中在三个不同的人群（位于孟加拉国、牙买加和巴基斯坦）中使用了标准研究程序和病例定义。本研究采用两阶段研究设计（筛选后进行专业评估），允许专业评估作为估计患病率的标准，即使是罕见疾病。因此，这里报告的患病率估计值在人群中具有高度的可比性，并且在人口调查中表现出异常强的有效性。在所有三个人群中，热性惊厥是最常见的惊厥史类型，其终生患病率点估计值为每1000人中10.9至62.8人。癫痫的终生患病率（复发性非诱发性癫痫发作）为每1000人5.8至15.5人。还报告了新生儿所有诱发性和所有非诱发性癫痫发作的终生患病率，以及活动性癫痫的患病率估计。
Although numerous estimates of the prevalence of seizure disorders in populations in the less developed world have now been published, these estimates are difficult to interpret due to lack of comparability of study methods and criteria for case definition. The results reported in this paper are from a large, collaborative study of disabilities in 2- to 9-year-old children in which standard research procedures and case definitions were used in three diverse populations (located in Bangladesh, Jamaica and Pakistan). A two-phase study design (screening followed by professional evaluations) was used in this study allowing for the professional evaluation to serve as the criterion in the estimation of prevalence, even for rare disorders. As a result, the prevalence estimates reported here have a high degree of comparability across populations and exhibit unusually strong validity for population surveys. Febrile seizures were the most common type of seizure history in all three populations, with point estimates of lifetime prevalence ranging from 10.9 to 62.8 per 1000. The lifetime prevalence rates of epilepsy (recurrent unprovoked seizures) ranged from 5.8 to 15.5 per 1000. Lifetime prevalence rates of neonatal, all provoked and all unprovoked seizures, as well as estimates of the prevalence of active epilepsy, are also reported.