Use of pyridinium chlorochromate as methylene oxidant in 5,6-dihydropyrans: a practical one-step preparation of the anhydromevalonolactone
Use of pyridinium chlorochromate as methylene oxidant in 5,6-dihydropyrans: a practical one-step preparation of the anhydromevalonolactone
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DOI：
10.1021/jo00183a030
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发表时间：
1984-05
影响因子：
3.6
通讯作者：
F. Bonadies;R. D. Fabio;C. Bonini
中科院分区：
文献类型：
--
作者：
F. Bonadies;R. D. Fabio;C. Bonini
由隔离决定。 b 对表进行令人满意的元素分析。吸电子基团。总之，本方法将 PCC 的用途扩展到敏感底物（如 5, 6-二氢吡喃）中活化亚甲基的氧化，与其他氧化剂相比具有多个优点。温和的反应条件和良好的收率是该方法值得注意的特点。对相关线性或五元环烯丙醚的初步研究给出了有趣但往往不同的结果。
Determined by isolation. b Satisfactory elementalanalyses the table. electron-withdrawing group. In conclusion, the present method extends the use of PCC to theoxidation of activated methylene groups in sensitive substrates like 5, 6-dihydropyrans, with several advantages over other oxidizing agents. Mild reaction conditions and good yields are noteworthy features of the method. Preliminary studies on related linear or five-membered ring allylic ethers give interesting but often different results.