Good nutritional oral intake is associated with equal survival in demented and nondemented very old patients.
Good nutritional oral intake is associated with equal survival in demented and nondemented very old patients.
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DOI：
10.1111/j.1532-5415.1996.tb01409.x
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发表时间：
1996-11-01
影响因子：
6.3
通讯作者：
Trabucchi, M
中科院分区：
文献类型：
--
作者：
Franzoni, S;Frisoni, GB;Trabucchi, M
目的：为了评估非常老的痴呆症nursing home patients.DESIGN：A prospective cohort study.SETTING：A nursing home in北方意大利.MEASUREMENTS：人体测量和实验室营养指标和营养素摄入量进行了评估，在33痴呆症（年龄85.7 +/- 5.7岁）和25非痴呆症（年龄84.9 +/- 5.7岁）患者。在28个月的随访期内收集死亡率数据。Kaplan-Meyer分析和多变量考克斯比例风险models.Results：营养摄入量和营养状况与文献中的数据相比，痴呆症和非痴呆症患者相似，除了较小的三头肌皮褶厚度的痴呆症。每年每例受试者的累积年死亡率为0.23，痴呆（0.23）和非痴呆（0.22）相似。Kaplan-Meyer分析的未校正生存率在两组中相似，校正年龄、性别、认知、三头肌皮褶厚度和考克斯模型中的药物数量并没有改变关系。
OBJECTIVE: To evaluate the association of oral food intake with survival in very old demented nursing home patients.DESIGN: A prospective cohort-study.SETTING: A nursing home in northern Italy.MEASUREMENTS: Anthropometric and laboratory nutritional indicators and nutrient intake were assessed in 33 demented (age 85.7 +/- 5.7 years) and 25 nondemented (age 84.9 +/- 5.7 years) patients. Mortality data were collected over a 28-month follow-up period. Association of survival with dementia was estimated by Kaplan-Meyer analysis and multivariate Cox proportional hazard models.RESULTS: Nutrient intake and nutritional status were good compared with data in the literature and were similar in demented and nondemented patients, except for smaller triceps skinfold thickness in the demented. The cumulative annual death rate was 0.23 deaths per subject per year, similar in the demented (0.23) and the nondemented (0.22). Unadjusted survival by Kaplan-Meyer analysis was similar in the two groups, and correction for age, gender, cognition, triceps skinfold thickness, and number of drugs in a Cox model did not alter the relationship.CONCLUSIONS: Dementia developing in very old age is not necessarily associated with malnutrition and decreased life expectancy.