The role of panic-fear in comorbid asthma and panic disorder
The role of panic-fear in comorbid asthma and panic disorder
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DOI：
10.1016/j.janxdis.2008.06.005
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发表时间：
2009-03-01
影响因子：
10.3
通讯作者：
Lehrer, Paul M.
中科院分区：
文献类型：
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作者：
Feldman, Jonathan M.;Siddique, Mahmood I.;Lehrer, Paul M.
我们研究了惊恐-恐惧、惊恐障碍（PD）和成人哮喘患者哮喘结局的中介模型。PD采用焦虑障碍访谈量表进行评估。21例哮喘PD患者和27例仅哮喘患者完成了肺功能测定和问卷调查。尽管哮喘发作期间哮喘严重程度或身体症状没有差异，但哮喘-PD患者报告的疾病特异性和全身性恐慌恐惧比仅哮喘患者更大。疾病特异性恐慌-恐惧介导了PD与健康相关生活质量较差（包括哮喘引起的情绪障碍）之间的关系。疾病特异性恐慌-恐惧与更多的哮喘初级保健办公室就诊相关。哮喘-PD患者在哮喘发作期间比仅哮喘患者报告更大的易怒。普遍的恐慌-恐惧与哮喘导致的活动受限和哮喘急救药物的使用直接相关。这两种恐慌恐惧的测量都与哮喘的严重程度无关。在哮喘发作期间经历的恐慌恐惧可能是改善哮喘-PD患者健康相关生活质量的一个重要目标。(C)2008爱思唯尔有限公司版权所有。
We examined mediational models of panic-fear, panic disorder (PD), and asthma outcomes among adult asthma patients. PD was assessed by the Anxiety Disorders Interview Schedule. Twenty-one asthma-PD patients and 27 asthma-only patients completed spirometry and questionnaires. Asthma-PD patients reported greater illness-specific and generalized panic-fear than asthma-only patients, despite no differences in asthma severity or physical symptoms during asthma attacks. Illness-specific panic-fear mediated the relationship between PD and poorer health-related quality of life, including emotional disturbance due to asthma. Illness-specific panic-fear was associated with more primary care office visits for asthma. Asthma-PD patients reported greater irritability during asthma attacks than asthma-only patients. Generalized panic-fear was directly associated with restriction of activities due to asthma and use of rescue medication for asthma. Neither measure of panic-fear was associated with asthma severity. Panic-fear experienced during asthma attacks may be an important area to target for improving health-related quality of life among asthma-PD patients. (C) 2008 Elsevier Ltd. All rights reserved.