Inositol Phosphates and Lipids
Inositol Phosphates and Lipids
复制标题
磷酸肌醇和脂质
DOI:
10.1007/978-1-60327-175-2_12
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发表时间:
2010
期刊:
影响因子:
--
通讯作者:
Cooke F
中科院分区:
文献类型:
--
作者:
Cooke F
The phosphoinositide 3-kinase (PI3K) family catalyses the addition of a phosphate group to the D-3 position of polyphosphoinositides (PPIn). Since the discovery in the late 80s that phosphatidylinositol is phosphorylated in the D-3 position in eukaryotic cells, there has been an explosion of interest in these PPIn. Although the four D-3 PPIn (phosphatidylinositol 3-phophate (PtdIns3P), PtdIns(3,4)P2, PtdIns(3,5)P2, and PtdIns(3,4,5)P3) represent only a small proportion of PPIn, production of D-3 PPIn is required for an ever-increasing number of processes. Measurement of the PPIn levels in intact cells cultured cells has been vital to our understanding of the metabolism and function of these important signalling molecules; methods are described herein that allow measurement of PPIn levels in cultured cells, with emphasis on the 3-OH PPIn.
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影响因子:
--
作者:
Draskovic, Petra;Saiardi, Adolfo;Podobnik, Marjetka
通讯作者:
Podobnik, Marjetka
DOI:
10.1042/bj3610525
发表时间:
2002
期刊:
The Biochemical journal
影响因子:
--
作者:
Wendy A. Kimber;L. Trinkle-Mulcahy;P. Cheung;M. Deák;Louisa J. Marsden;A. Kieloch;S. Watt;R. Javier;A. Gray;C. Downes;J. Lucocq;D. Alessi
通讯作者:
Wendy A. Kimber;L. Trinkle-Mulcahy;P. Cheung;M. Deák;Louisa J. Marsden;A. Kieloch;S. Watt;R. Javier;A. Gray;C. Downes;J. Lucocq;D. Alessi
影响因子:
9.2
作者:
K. Venkateswarlu;P. Oatey;J. Tavaré;P. Cullen
通讯作者:
P. Cullen
影响因子:
4.8
作者:
Yong Zhan;J. Virbasius;Xi Song;Darcy P. Pomerleau;G. Zhou
通讯作者:
G. Zhou
影响因子:
14.8
作者:
Azevedo, Cristina;Saiardi, Adolfo
通讯作者:
Saiardi, Adolfo