HAS THERE BEEN A DECLINE IN SUBARACHNOID HEMORRHAGE MORTALITY

HAS THERE BEEN A DECLINE IN SUBARACHNOID HEMORRHAGE MORTALITY
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DOI:
10.1161/01.str.20.6.718
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发表时间:
1989-06-01
期刊:
影响因子:
8.3
通讯作者:
OFALLON, WM
OFALLON, WM
中科院分区:
医学1区
文献类型:
--
作者:
INGALL, TJ;WHISNANT, JP;OFALLON, WM

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我们研究了 1945 年至 1984 年 40 年间美国明尼苏达州罗切斯特市人口的蛛网膜下腔出血情况。罗切斯特市蛛网膜下腔出血的平均年发病率一直稳定在每 10 万人中约 11 例。特定年龄的发病率随着年龄的增长而增加。然而,罗切斯特市蛛网膜下腔出血的年平均死亡率却呈下降趋势,从1955-1964年的每10万人6.8人下降到1975-1984年的4.3人。这可能是由于病死率从 1945-1974 年的 57% 下降到 1975-1984 年的 42% (p = 0.10)。这种下降趋势在美国白人男性和女性蛛网膜下腔出血的年死亡率中也很明显。病死率提高的原因尚不清楚,但可能与管理方式的变化有关。从蛛网膜下腔出血到手术的时间间隔从1975-1979年的平均12天减少到1980-1984年的2天,并且在那些幸存并接受医疗护理的患者中,更多的患者在1980-1984年接受了某种形式的医疗。这些变化是否导致病死率下降尚不确定。
We studied subarachnoid hemorrhage in the population of Rochester, Minnesota [USA] for the 40-year period from 1945 through 1984. The average annual incidence rate of subarachnoid hemorrhage in Rochester has remained constant at approximately 11 per 100,000 population. Age-specific incidence rates increased with age. However, the average annual mortality rate for subarachnoid hemorrhage in Rochester has shown a decreasing trend, from 6.8 per 100,000 population in 1955-1964 to 4.3 in 1975-1984. It is likely that this is due to a decrease in case-fatality rates from 57% in 1945-1974 to 42% in 1975-1984 (p = 0.10). This decreasing trend was also evident in annual mortality rates from subarachnoid hemorrhage for US white men and women. The reason for the improved case-fatality rate is unclear, but it may be related to changes in management. The interval from onset of subarachnoid hemorrhage to surgery decreased from a median of 12 days in 1975-1979 to 2 days in 1980-1984, and of those who survived to receive medical attention, more patients received some form of medical treatment in 1980-1984., Whether either or both of these changes have led to the decrease in the case-fatality rate is uncertain.