DOES THE DESATURASE‐2 LOCUS IN DROSOPHILA MELANOGASTER CAUSE ADAPTATION AND SEXUAL ISOLATION?
DOES THE DESATURASE‐2 LOCUS IN DROSOPHILA MELANOGASTER CAUSE ADAPTATION AND SEXUAL ISOLATION?
复制标题
果蝇中的去饱和酶-2 基因座是否会导致适应和性隔离？
DOI：
10.1111/j.0014-3820.2006.tb01106.x
复制
发表时间：
2006
期刊：
影响因子：
3.3
通讯作者：
S. Elwyn
中科院分区：
文献类型：
--
作者：
J. Coyne;S. Elwyn
黑腹果蝇（Drosophila melanogaster）的去饱和酶2 （desat2）位点有两个等位基因，其频率在地理上存在差异：一个（“Z”等位基因）主要在东非和加勒比地区发现，另一个（“M”等位基因）出现在世界其他地区。有人认为，这些等位基因不仅导致种族间的性隔离，而且它们的分布反映了对气候的不同适应：Z等位基因被认为适应热带条件，而M等位基因则适应温带条件。因此，这被视为生殖隔离演变为适应的多效副产品的一个例子。在这里，我们重新研究这种假定的气候适应，使用转基因系在其desat2等位基因的性质不同。我们无法重复先前的结果，表明M等位基因的携带者比Z等位基因的携带者更抗寒，更不耐饥饿。因此，这些等位基因的分布是否反映了涉及气候的自然选择是值得怀疑的。对转基因品系的交配研究显示了由于死亡导致性隔离的一些证据2。然而，对其他野生型系的研究，以及对性隔离性质的观察表明，这一结论——以及这一基因座与不同种族间交配歧视之间的关系——可能也值得怀疑
Abstract The desaturase‐2 (desat2) locus of Drosophila melanogaster has two alleles whose frequencies vary geographically: one (the “Z” allele) is found primarily in east Africa and the Caribbean, and the other (the “M” allele) occurs in other parts of the world. It has been suggested that these alleles not only cause sexual isolation between races, but that their distribution reflects differential adaptation to climate: Z alleles are supposedly adapted to tropical conditions and M alleles to temperate ones. This has thus been viewed as a case of reproductive isolation evolving as a pleiotropic byproduct of adaptation. Here we reinvestigate this presumed climatic adaptation, using transgenic lines differing in the nature of their desat2 alleles. We were unable to replicate earlier results showing that carriers of M alleles are uniformly more cold resistant and less starvation resistant than carriers of Z alleles. It is thus doubtful whether the distribution of these alleles reflects natural selection involving climate. Mating studies of transgenic lines show some evidence for sexual isolation due to desat2. However, work on other, wild‐type lines, as well as observations on the nature of sexual isolation, suggest that this conclusion‐and thus the relationship between this locus and mating discrimination between races of D. melanogaster‐may also be doubtful
登录
查看更多内容
影响因子：
56.9
作者：
COYNE, JA;CRITTENDEN, AP;MAH, K
通讯作者：
MAH, K
DOI：
10.1073/pnas.92.7.2519
发表时间：
1995-03-28
影响因子：
11.1
作者：
WU, CI;HOLLOCHER, H;WU, ML
通讯作者：
WU, ML
影响因子：
10.5
作者：
Rong, YKS;Titen, SW;Golic, KG
通讯作者：
Golic, KG
果蝇和模拟果蝇之间信息素碳氢化合物差异的遗传学。
影响因子：
3.3
作者：
Coyne,JA
通讯作者：
Coyne,JA
影响 Drosophila mauritiana 和 D. sechellia 之间性隔离的信息素差异的遗传学。
影响因子：
3.3
作者：
Coyne,JA;Charlesworth,B
通讯作者：
Charlesworth,B