Pathways from fertility history to later life health: Results from analyses of the English Longitudinal Study of Ageing
Pathways from fertility history to later life health: Results from analyses of the English Longitudinal Study of Ageing
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DOI：
10.4054/demres.2015.32.4
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发表时间：
2015-01-09
影响因子：
2.1
通讯作者：
Read, Sanna
中科院分区：
文献类型：
--
作者：
Grundy, Emily;Read, Sanna
先前的研究表明生育史与晚年健康之间存在关联。无子女者、大家庭成员和初为人父母者的死亡率通常高于有两个或三个孩子的父母，健康状况也较差。这些协会被假设为反映了一系列的生物社会影响，但基本机制知之甚少。EQUITIVESTo确定途径从生育史到以后的生活健康检查调解通过健康相关的行为，社会支持和应变，和财富。此外，检查调解通过allostatic负荷-多系统的物理失调的指标，假设是一个结果的慢性stress. METHODS生育史，介质和结果之间的关联进行了分析，使用路径模型。数据来自英国老龄化纵向研究。研究的结果是基于9种生物标志物和自我报告的限制活动的长期疾病的非稳态负荷的测量。
BACKGROUNDPrevious research shows associations between fertility histories and later life health. The childless, those with large families, and those with a young age at entry to parenthood generally have higher mortality and worse health than parents of two or three children. These associations are hypothesised to reflect a range of biosocial influences, but underlying mechanisms are poorly understood.OBJECTIVESTo identify pathways from fertility histories to later life health by examining mediation through health-related behaviours, social support and strain, and wealth. Additionally to examine mediation through allostatic load - an indicator of multisystem physical dysregulation, hypothesised to be an outcome of chronic stress.METHODSAssociations between fertility histories, mediators, and outcomes were analysed using path models. Data were drawn from the English Longitudinal Study of Ageing. Outcomes studied were a measure of allostatic load based on 9 biomarkers and self-reported long-term illness which limited activities.RESULTSEarly parenthood (