Chest CT Findings in Cases from the Cruise Ship Diamond Princess with Coronavirus Disease (COVID-19)
Chest CT Findings in Cases from the Cruise Ship Diamond Princess with Coronavirus Disease (COVID-19)
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DOI：
10.1148/ryct.2020200110
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发表时间：
2020-04-01
期刊：
影响因子：
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通讯作者：
Uwabe, Yasuhide
中科院分区：
文献类型：
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作者：
Inui, Shohei;Fujikawa, Akira;Uwabe, Yasuhide
目的：目的评价2019年新冠肺炎（COVID-19）患者钻石公主号邮轮环境同质队列的胸部CT表现。材料和方法：本回顾性研究包括104例经逆转录聚合酶链反应（RT-PCR）结果证实的COVID-19患者（平均年龄62岁6 16 [标准差]，范围25-93岁）。回顾CT图像，计算每个肺叶和整个肺的CT严重程度评分。结果：104例患者中，76例（73%）无症状，其中41例（54%）CT表现为肺部阴影。28例（27%）有症状，其中22例（79%）有异常CT表现。有症状病例的CT显示肺部阴影和气道异常的频率高于无症状病例[肺部阴影; 22（79%）vs 41（54%），气道异常; 14（50%）vs 15（20%）]。无症状病例显示磨玻璃样阴影（GGO）多于实变（83%），而有症状病例更常显示实变多于GGO（41%）。有症状病例的CT严重程度评分高于无症状病例，尤其是下叶[有症状病例vs无症状病例;右下叶：2 6 1（0 -4）vs 1 6 1（0-4）;左下叶：2 6 1（0-4）vs 1 6 1（0-3）;总分：7 6 5（1-17）vs 4 6 2（1-11）]。结论：本研究记录了COVID-19病例中亚临床CT改变的高发生率。与有症状病例相比，无症状病例CT表现为GGO多于实变，病变范围较轻。
Purpose: To evaluate the chest CT findings in an environmentally homogeneous cohort from the cruise ship Diamond Princess with coronavirus disease 2019 (COVID-19).Materials and Methods: This retrospective study comprised 104 cases (mean age, 62 years 6 16 [standard deviation], range, 25-93 years) with COVID-19 confirmed with reverse-transcription polymerase change reaction findings. CT images were reviewed, and the CT severity score was calculated for each lobe and the entire lung. CT findings were compared between asymptomatic and symptomatic cases.Results: Of 104 cases, 76 (73%) were asymptomatic, 41 (54%) of which had lung opacities on CT. Twenty-eight (27%) cases were symptomatic, 22 (79%) of which had abnormal CT findings. Symptomatic cases showed lung opacities and airway abnormalities on CT more frequently than asymptomatic cases [lung opacity; 22 (79%) vs 41 (54%), airway abnormalities; 14 (50%) vs 15 (20%)]. Asymptomatic cases showed more ground-glass opacity (GGO) over consolidation (83%), while symptomatic cases more frequently showed consolidation over GGO (41%). The CT severity score was higher in symptomatic cases than asymptomatic cases, particularly in the lower lobes [symptomatic vs asymptomatic cases; right lower lobe: 2 6 1 (0-4) vs 1 6 1 (0-4); left lower lobe: 2 6 1 (0-4) vs 1 6 1 (0-3); total score: 7 6 5 (1-17) vs 4 6 2 (1-11)].Conclusion: This study documented a high incidence of subclinical CT changes in cases with COVID-19. Compared with symptomatic cases, asymptomatic cases showed more GGO over consolidation and milder extension of disease on CT.