Toward an Ideal Synthesis of (Bio)molecules through Direct Arene Assembling Reactions
Toward an Ideal Synthesis of (Bio)molecules through Direct Arene Assembling Reactions
复制标题
DOI：
10.1246/bcsj.20160365
复制
发表时间：
2017-04
影响因子：
4
通讯作者：
Junichiro Yamaguchi;K. Itami
中科院分区：
文献类型：
--
作者：
Junichiro Yamaguchi;K. Itami
使用过渡金属催化剂对芳香族化合物进行C-H（杂）芳基化作为构建（杂）联芳基序的下一代偶联方法，引起了合成化学界的广泛关注。本文描述了我们最近在过渡金属催化芳香族 C-H 芳基化方面取得的成就及其在生物活性分子合成中的应用。
C–H (hetero)arylation of aromatic compounds using transition-metal catalysts has garnered much attention from the synthetic chemistry community as a next-generation coupling method for constructing (hetero)biaryl motifs. This account describes our recent achievements in transition-metal-catalyzed aromatic C–H arylation and its applications to the synthesis of bioactive molecules.