Giant cell myocarditis: an autoimmune disease?
Giant cell myocarditis: an autoimmune disease?
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巨细胞心肌炎：一种自身免疫性疾病？
DOI：
10.1016/0002-8703(88)90505-4
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发表时间：
1988
影响因子：
4.8
通讯作者：
J. Dupond
中科院分区：
文献类型：
--
作者：
P. Humbert;Rene Faryre;Dominique Fellman;Jean F Bassand;J. Dupond
右心房和心室之间的2号连接处。肿瘤无蒂，完全阻塞三尖瓣，并侵犯室间隔和心包表面。大部分肿瘤被切除。术后，患者接受放疗和化疗。然而，她变得恶病质，并于1985年6月7日去世。尸检时可见肿瘤残留，并转移至心包、大脑、小脑和双侧卵巢。最常见的恶性心脏肿瘤是血管肉瘤，占此类肿瘤的7.3%~ 13%，最常见的是右心房。我们的病人因为心脏病做了心脏活检。由于心包积液的细胞学检查结果为阴性，因此迫切需要确认右心房肿瘤的诊断。病理组织学诊断为右心房血管肉瘤。超微结构的研究结果表明，血管生成的特点，在这个肿瘤，如杨等1。5我们还没有能够找到以前的报告，心脏肿瘤的诊断心脏活检。心脏血管肉瘤的预后很差。6如果在病程早期通过活检做出诊断，则可以尽快选择并实施最合适的治疗。
Number 2 junction between the right atrium and the ventricle. The tumor had no stalk and completely obstructed the tricuspid valve, and invaded the ventricular septum and the pericardial surface. Most of the tumor was resected. Postoperatively, the patient received radiotherapy and chemotherapy. However, she became cachectic and died on June 7, 1985. Remnants of the tumor, with metastases to the pericardium, cerebrum, cerebellum, and both ovaries, were seen at autopsy.The most common variety of malignant cardiac tumors is angiosarcoma, which constitutes 7.3% to 13% of such tumors3p4 and is most commonly localized in the right atrium. A cardiac biopsy was performed in our patient because of th. e urgent need to confirm the diagnosis of right atria1 tumor and because cytologic examination of the pericardial effusion gave negative results. This biopsy yielded a histopathologic diagnosis of angiosarcoma of the right atrium. Results of ultrastructural study showed angiogenetic features in this tumor, as described by Yang et a1. 5 We have not been able to find previous reports on the diagnosis of cardiac tumors by cardiac biopsy. The prognosis of cardiac angiosarcoma is very poor. 6 If the diagnosis is made by biopsy early in the course of the disease, the most appropriate treatment can be selected and administered as soon as possible.