Development of the crosslinking reactions to RNA triggered by oxidation
Development of the crosslinking reactions to RNA triggered by oxidation
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DOI：
10.1039/c3cc49463b
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发表时间：
2014-01-01
影响因子：
4.9
通讯作者：
Nagatsugi, Fumi
中科院分区：
文献类型：
--
作者：
Kusano, Shuhei;Haruyama, Takuya;Nagatsugi, Fumi
A novel crosslink-forming nucleobase, 2-amino-6-(1-ethylthiovinyl)-purine (ATVP), which is triggered by the oxidation of sulfide to sulfoxide, has been developed. The oxidation of ATVP within the duplex proceeded with H2O2 and FeCl2. We have successfully developed the crosslinking reactions activated by oxidation.
