The Motor Unit Number Index (MUNIX) in sarcopenic patients
The Motor Unit Number Index (MUNIX) in sarcopenic patients
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DOI：
10.1016/j.exger.2013.01.011
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发表时间：
2013-04-01
影响因子：
3.9
通讯作者：
Sieber, C. C.
中科院分区：
文献类型：
--
作者：
Drey, M.;Groesch, C.;Sieber, C. C.
前言：肌肉减少症的病因尚不完全清楚。讨论了多因素病因。神经退行性方面在肌肉减少症的发生，如运动神经元的损失，尚未被探索到足够的程度。方法：运动单元数指数（Motor Unit Number Index， MUSIX）是一种利用复合肌肉动作电位（CMAP）和表面肌电干涉图（SIP）来评估运动单元（Motor Unit size Index， MUSIX）数量和大小的方法。应用该方法对27例肌肉减少症患者的右手鱼际下肌进行了研究。结果：所有肌减少症患者的平均MUNIX（111 +/- 51）介于健康人的平均MUNIX和ALS患者的平均MUNIX之间。25%的肌肉减少症患者表现出两种MUNIX （100 μ V）的病理值。相关性强(r= 0.75, p
Introduction: The cause of sarcopenia is still not fully understood. A multifactorial aetiology is discussed. Neurodegenerative aspects in the genesis of sarcopenia, such as loss of motoneurons, have not yet been explored to a sufficient extent.Method: The Motor Unit Number Index (MUNIX) is a method for assessing the number and size (Motor Unit Size Index - MUSIX) of Motor Units (MUs) using the Compound Muscle Action Potential (CMAP) and the Surface electromyographic Interference Pattern (SIP). This method was used to study the hypothenar muscle in the right hand of 27 sarcopenic patients.Results: The mean MUNIX (111 +/- 51) of all investigated sarcopenic patients lies between the mean MUNIX of healthy persons and the mean MUNIX of ALS patients. 25% of sarcopenic patients exhibit pathologic values for both MUNIX ( 100 mu V). A strong correlation (r= 0.75, p