Hemodynamic Change In A Cerebral Aneurysm Treated By Double Stenting Technique
Hemodynamic Change In A Cerebral Aneurysm Treated By Double Stenting Technique
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双支架技术治疗脑动脉瘤的血流动力学变化
DOI：
10.1109/embc.2018.8512461
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
Murayama Yuichi
中科院分区：
文献类型：
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作者：
Uchiyama Yuya;Takao Hiroyuki;Suzuki Takashi;Fujimura Soichiro;Tanaka Kazutoshi;Otani Katharina;Hayakawa Motoharu;Ishibashi Toshihiro;Fukudome Koji;Mamori Hiroya;Yamamoto Makoto;Murayama Yuichi
脑动脉瘤破裂通常会导致蛛网膜下腔出血，这是一种危及生命的疾病，死亡率很高。较大的动脉瘤被认为更容易破裂，因此应该进行治疗。近年来，血流导向装置（FD）被广泛用于治疗大型或宽颈动脉瘤。然而，由于其不充分的流动扰动，因此难以通过部署单个FD来治疗它们。为了克服这一问题，有时采用双支架技术，目的是提高血流速度降低的效果。在这项研究中，我们使用计算流体动力学（CFD）来研究部署虚拟FD时动脉瘤中的血流动力学变化。结果表明，动脉瘤内的血流场的特性没有改变后，部署一个单一的FD，但发生了很大的变化后，部署两个FD。此外，与未植入支架相比，当展开两个FD而不是一个FD时，远离载瘤动脉的平面处的动脉瘤囊中的速度降低从25.9%增加到92.8%。双支架植入术可有效降低大或宽颈动脉瘤的血流速度。
Rupture of cerebral aneurysms often causes subarachnoid hemorrhage which is a life-threatening condition with high mortality rates. Larger aneurysms are believed to be more likely to rupture and should therefore be treated. Recently, flow diverters (FDs) are widely used to treat large or wide neck aneurysms. However, it can be difficult to treat them by deployment of a single FD because of its insufficient flow disturbance. To overcome this problem, double stenting technique is sometimes applied with the aim to improve the effect of blood velocity reduction. In this study, we used computational fluid dynamics (CFD) to investigate the hemodynamic changes in an aneurysm when deploying virtual FDs. The results showed that the characteristics of the blood flow field inside the aneurysm did not changed much after the deployment of a single FD but underwent a large change after the deployment of two FDs. Furthermore, the velocity reduction in the aneurysm sac at a plane away from the parent artery increased from 25.9% to 92.8% when two FDs were deployed instead of one compared to no stenting. Double stenting was effective to decrease blood velocity in large or wide neck aneurysms.