Preliminary Results of Prostate Vaporization in the Treatment of Benign Prostatic Hyperplasia by Using a 200-W High-intensity Diode Laser
Preliminary Results of Prostate Vaporization in the Treatment of Benign Prostatic Hyperplasia by Using a 200-W High-intensity Diode Laser
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DOI：
10.1016/j.urology.2009.09.033
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发表时间：
2010-03-01
期刊：
影响因子：
2.1
通讯作者：
Lee, Wei-Chia
中科院分区：
文献类型：
--
作者：
Chen, Chien-Hsu;Chiang, Po-Hui;Lee, Wei-Chia
目的评价200 W高强度半导体激光治疗良性前列腺增生症的有效性和安全性。方法采用侧射激光光纤（半导体激光：功率150-200 W;波长980 nm; Limmer，德国）汽化前列腺。在基线以及1个月和6个月的随访期后评估以下参数：国际前列腺症状评分、最大尿流率、排尿后残余尿量和生活质量评分。前列腺体积和前列腺特异性抗原水平进行了评估，在基线和6个月postoperatives.Results本研究包括55例诊断为下尿路症状继发于BPH，谁是治疗2007年12月和2008年7月之间。复吸率为10.9%。这些患者均不需要输血或有经尿道切除综合征。与各自的基线值相比，在1个月和6个月随访时，观察到国际前列腺症状评分、Q（max）、排尿后残余尿量和生活质量评分值有统计学显著性改善（P <0.001）。8例患者（8/55，14.5%）出现一过性急迫性尿失禁。8例术后数周或数月内膀胱镜检查见坏死组织脱落。再次治疗率（二次经尿道前列腺电切术）为7.3%。结论从我们的初步数据来看，很明显，半导体激光前列腺切除术可以达到良好的止血效果，并立即缓解梗阻性排尿症状。然而，术后刺激症状和坏死组织脱落仍然是需要解决的重要问题。泌尿学75：658-663，2010年。(C)2010年爱思唯尔公司
OBJECTIVES To evaluate the efficacy and safety of a 200-W high-intensity diode laser in the treatment of benign prostatic hyperplasia.METHODS The prostate was vaporized by using a side-firing laser fiber (diode laser: power, 150-200 W; wavelength, 980 nm; Limmer, Germany). The following parameters were assessed at baseline, and after a follow-up period of 1- and 6 months: International Prostate Symptom Score, maximum uroflow rate, postvoid residual urine volume, and quality of life score. Prostate volume and prostate-specific antigen levels were assessed at baseline and 6 months postoperatively.RESULTS This study included 55 patients diagnosed with lower urinary tract symptoms secondary to BPH, who were treated between December 2007 and July 2008. The recatheterization rate was 10.9%. None of these patients required a blood transfusion or had transurethral resection syndrome. Statistically significant improvements (P < .001) were observed in the values of International Prostate Symptom Score, Q(max), postvoid residual urine volume, and quality of life score at 1- and 6 months of follow-up as compared with the respective baseline values. Transient urge incontinence was noted in 8 patients (8/55, 14.5%). Sloughing of necrotic tissues was observed on cystoscopy in 8 patients within several weeks or months after the operation. The retreatment rate (secondary transurethral resection of the prostate) was 7.3%.CONCLUSIONS From our preliminary data, it was evident that diode laser prostatectomy can achieve excellent hemostasis, and provide immediate relief from obstructive voiding symptoms. However, the postoperative irritative symptoms and sloughing of necrotic tissues remained to be an important issue that needed to be resolved. UROLOGY 75: 658-663, 2010. (C) 2010 Elsevier Inc.