Interleukins 2, 6, and 8 levels in human gingival sulcus during orthodontic treatment

Interleukins 2, 6, and 8 levels in human gingival sulcus during orthodontic treatment
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DOI:
10.1016/j.ajodo.2005.12.027
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发表时间:
2006-07-01
影响因子:
3
通讯作者:
Hamamci, Orhan
Hamamci, Orhan
中科院分区:
医学2区
文献类型:
--
作者:
Basaran, Guvenc;Ozer, Torun;Hamamci, Orhan

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前言:本研究的目的是测定牙齿移动过程中白介素2、白介素6和白介素8的水平,并测试它们在标准正畸治疗的不同治疗阶段所使用的水平力量和远中力量是否存在差异。方法:15例患者,其中女性9例,男性6例,年龄15~19岁,平均16.7±-2.3岁。每个人都接受了一次专业的口腔卫生培训,并接受了口腔卫生指导。两个月后,放置了固定的正畸矫治器。患者在基线、第7天和第21天以及牙齿水平时被观察到。在6个月时记录远距部队的基线分数。同时记录治疗6个月后第7天和第21天的评分。结果:牙周组织中IL-2、IL-6、IL-8的含量和牙周组织中IL-2、IL-6、IL-8的含量均有不同程度的升高。
Introduction: The aims of this study were to determine levels of interleukins 2, 6, and 8 during tooth movement, and test whether they differ from each other with leveling and distalization forces used in various treatment stages of standard orthodontic therapy. Methods: Fifteen patients (9 female, 6 male; ages, 15-19 years; mean age, 16.7 +/- 2.3 years) participated in this study. Each underwent a session of professional oral hygiene and received oral hygiene instructions. Two months later, a fixed orthodontic appliance was placed. The patients were seen at baseline, at days 7 and 21, and as the teeth were leveled. Records of the baseline scores for the distalization forces were taken at the sixth month. Scores of days 7 and 21 after 6 months of the distalization treatment were also recorded. Results: Increases were seen in the volume of gingival crevicular fluid and the concentrations of interleukins 2, 6, and 8. Conclusions: Leveling and distalization of the teeth evoke increases in interleukins 2, 6, and 8 levels in the periodontal tissues that can be detected in gingival crevicular fluid.