Wegener's granulomatosis and polymorphic reticulosis--two diseases or one? Experience with 90 patients.
Wegener's granulomatosis and polymorphic reticulosis--two diseases or one? Experience with 90 patients.
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韦格纳肉芽肿病和多形性网状细胞增多症——两种疾病还是一种？
DOI：
10.1001/archotol.1981.00790390007003
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
L. Weiland
中科院分区：
文献类型：
--
作者：
T. J. Mcdonald;R. Deremee;L. Weiland
我们对50例韦格纳肉芽肿病和40例多形性网状细胞增多症的经验使我们能够比较这两种疾病的临床和组织病理学。虽然这些条件在某些方面是相似的，但它们是独立和可分离的实体。组织学特征可能是最有用的鉴别诊断标准。韦格纳肉芽肿病的特征是血管炎和坏死性肉芽肿的存在，而多形性网状细胞增多症的典型特征是混合淋巴浸润和血管中心性生长模式。医生应该意识到这两种疾病之间的差异，并了解这两种疾病的影响。
Our experience with 50 patients with Wegener's granulomatosis and 40 patients with polymorphic reticulosis allowed us to compare these two disorders both clinically and histopathologically. Although these conditions are similar in some respects, they are separate and separable entities. The histologic features may be the most useful criteria for differentiation. Wegener's granulomatosis is characterized by the presence of vasculitis and necrotizing granulomas, whereas polymorphic reticulosis is typified by a mixed lymphoid infiltrate with an angiocentric growth pattern. The physician should be aware of the differences between these two disorders and should understand the implications of both conditions.