No evidence for intra-segment recombination of 2009 H1N1 influenza virus in swine
No evidence for intra-segment recombination of 2009 H1N1 influenza virus in swine
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DOI：
10.1016/j.gene.2011.10.041
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发表时间：
2012-02-25
期刊：
影响因子：
3.5
通讯作者：
Vijaykrishna, Dhanasekaran
中科院分区：
文献类型：
--
作者：
Boni, Maciej F.;Smith, Gavin J. D.;Vijaykrishna, Dhanasekaran
Hao（2011）报道，三种甲型猪流感病毒的PB2基因很可能是通过亲本毒株之间的同源重组产生的。然而，我们表明郝的观察是由于缺乏适当的进化背景而产生的不正确的分类群采样的产物。通过严格的系统发育分析，我们解释了这些污渍的进化起源，并证实缺乏任何统计支持的片段内重组。(C) 2011 Elsevier B.V.版权所有
Hao (2011) reported that the PB2 genes of three swine influenza A viruses were likely generated through homologous recombination between two closely related parental strains. However, we show that Hao's observation is an artifact of incorrect taxon sampling arising through the lack of an appropriate evolutionary context. Through rigorous phylogenetic analyses we explain the evolutionary origins of these stains and confirm the lack of any statistical support for intra-segmental recombination. (C) 2011 Elsevier B.V. All rights reserved.