An imported case of acute pulmonary coccidioidomycosis in an Italian traveller
An imported case of acute pulmonary coccidioidomycosis in an Italian traveller
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DOI：
10.1007/s15010-014-0614-4
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发表时间：
2014-10-01
期刊：
影响因子：
7.5
通讯作者：
Nicastri, E.
中科院分区：
文献类型：
--
作者：
Corpolongo, A.;Giancola, M. L.;Nicastri, E.
球孢子菌病是由球孢子菌属物种引起的真菌感染，其在美国西南部地区、墨西哥北方以及中美洲和南美洲的一些地区的沙漠中是地方性的。我们描述了一例肺球孢子菌病在49岁的意大利男子谁来到我们医院发热和关节和肌肉疼痛10天后，他从委内瑞拉返回意大利。电脑断层显示双侧肺多发结节及纵隔淋巴结肿大。通过血清学试验诊断为肺球孢子菌病，立即开始使用氟康唑。患者在2周内改善，治疗6个月后完全临床恢复。该病例似乎是未经血清学证实的大规模疫情的一部分。为了提供早期诊断和治疗，医疗保健提供者应该意识到球孢子菌病，即使是从流行地区短途旅行回家的旅行者。
Coccidioidomycosis is a fungal infection caused by the Coccidioides species, which is endemic in the deserts of the southwestern region of the United States, northern Mexico, and in some areas of Central and South America. We describe a case of pulmonary coccidioidomycosis in a 49-year-old Italian man who came to our hospital with fever and joint and muscle pain 10 days after his return to Italy from Venezuela. Computer Tomography revealed multiple bilateral pulmonary nodules with mediastinal lymphadenopathy. Pulmonary coccidioidomycosis was diagnosed by a serological test, and fluconazole was immediately started. The patient improved within 2 weeks, with complete clinical recovery after 6 months of therapy. This case appears to be part of a large serologically unconfirmed outbreak. In order to provide early diagnosis and treatment, healthcare providers should be aware of coccidioidomycosis, even in travellers returning home from short trips to endemic areas.