Trends in cancer mortality in the elderly in Japan, 1970-2007
Trends in cancer mortality in the elderly in Japan, 1970-2007
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DOI：
10.1093/annonc/mdp303
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发表时间：
2010-02-01
影响因子：
50.5
通讯作者：
Sakamoto, N.
中科院分区：
文献类型：
--
作者：
Yang, L.;Fujimoto, J.;Sakamoto, N.
目的：本研究的主要目的是描述1970- 2007年日本65-84岁老年人的癌症死亡率和趋势。材料和方法：使用5年年龄间隔的年龄别死亡率和基于标准世界人口年龄分布的权重，通过直接法计算标准化死亡率。joinpoint回归模型被用来描述trends. Results的变化：对于所有癌症合并，死亡率在65-84岁在2000-2007年期间为1145.13（每10万人口）的男性和461.93（每10万）的女性。在过去10年中，男女的死亡率都有所下降。这些有利的趋势主要是由于老年男性中三种主要癌症[肺癌、胃癌和结直肠癌（CRC）]以及老年女性中三种最常见癌症中的两种的死亡率下降（胃癌和结直肠癌），再加上女性肺癌死亡率的平稳。目前研究中基于人口的数据强调了日本老年人癌症研究和预防的重要性，以减少越来越多的老年人的额外癌症负担。
Objective: The primary objective of this study is to describe cancer mortality rates and trends among Japanese elderly aged 65-84 years for the period 1970-2007.Materials and methods: Age-standardized mortality rates were calculated by the direct method using age-specific mortality rates at 5-year age intervals and weights based on the age distribution of the standard world population. The joinpoint regression model was used to describe changes in trends.Results: For all cancers combined, the mortality rate at age 65-84 years during 2000-2007 was 1145.13 (per 100 000 population) for men and 461.93 (per 100 000) for women. Mortality rates have declined in the past 10 years in both sexes. These favorable trends were driven largely by decreases in mortality for three leading cancers in the elderly men [lung, stomach and colorectal cancer (CRC)] and for two of the three most common cancers in the elderly women (stomach and CRC), combined with a leveling off of death rate from lung cancer in women.Conclusion: The population-based data in the current study underscore the importance of cancer research and prevention for the older segment in Japan to reduce the additional cancer burden among the growing number of elderly persons.