Oxidation State-Specific Fluorescent Method for Palladium(II) and Platinum(IV) Based on the Catalyzed Aromatic Claisen Rearrangement
Oxidation State-Specific Fluorescent Method for Palladium(II) and Platinum(IV) Based on the Catalyzed Aromatic Claisen Rearrangement
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DOI：
10.1021/ja8065539
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发表时间：
2008-12-10
影响因子：
15
通讯作者：
Koide, Kazunori
中科院分区：
文献类型：
--
作者：
Garner, Amanda L.;Koide, Kazunori
活性药物成分和保健品被氧化形式的钯和铂污染是一个重要的问题。我们报道了一种基于催化芳香clisen重排的荧光探针，能够检测Pd-II和Pt-IV。使用该探针，我们可以荧光检测功能化有机化合物中的Pd-III和pt -0-水中的Pt-IV，而无需样品预处理。该方法可广泛应用于制药工业、环境和Pd/Pt质量控制。
Contamination of active pharmaceutical ingredients and healthcare products with oxidized forms of palladium and platinum are important problems. We report a convenient fluorogenic probe based on the catalyzed aromatic Claisen rearrangement capable of detecting Pd-II and Pt-IV. Using this probe, we can fluorescentty detect Pd-III in functionalized organic compounds and Pt-IV in Pt-0-water without sample pretreatment. This method may find broad applications in the pharmaceutical industry, the environment, and Pd/Pt quality control.