Fluidized Bed Spray Granulation: Nucleation Studies with Steady-State Experiments

Fluidized Bed Spray Granulation: Nucleation Studies with Steady-State Experiments
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流化床喷雾造粒:稳态实验的成核研究

DOI:
10.1080/07373931003641495
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发表时间:
2010
期刊:
影响因子:
3.3
通讯作者:
M. Kind
M. Kind
中科院分区:
工程技术3区
文献类型:
--
作者:
G. Grünewald;B. Westhoff;M. Kind

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流态化喷雾造粒是一种从溶液、悬浮液或熔体中生产和配制粗粒的技术。为了连续和稳定地运行该工艺,从工艺中去除的产品颗粒必须被新的小颗粒所取代。成核率必须在一定的范围内;否则,过程行为将变得不稳定。在这项工作中,进行了底部喷雾结构的稳态实验,以确定工艺参数对内部成核率的影响。这些研究有助于理解内部形核对工艺参数的非线性依赖关系,并提供内部形核速率的定量数据。结果表明,内成核和粉尘整合是两种竞争机制。通过增加喷雾中的粉尘和液滴浓度来增强内部成核,从而导致两个分散相的团聚。另一方面,粘结剂在液体中的高浓度或大颗粒持有率等参数,有利于颗粒上的液滴沉积和粉尘集成,降低了液滴和粉尘的浓度,从而降低了内部成核。
Fluidized bed spray granulation is a technology for the production and formulation of coarse-grained granules from solutions, suspensions, or melts. In order to run the process continuously and stable, product particles removed from the process have to be replaced by new small granules. The nucleation rates have to be within certain limits; otherwise, the process behavior becomes unstable. In this work, steady-state experiments with a bottom-spray configuration were carried out to determine the influence of process parameters on internal nucleation rates. These investigations help to understand the nonlinear dependency of internal nucleation on process parameters and provide quantitative data of internal nucleation rates. It is shown that internal nucleation and dust integration are competitive mechanisms. Internal nucleation is enhanced by conditions that increase dust and drop concentrations in the spray resulting in agglomeration of the two disperse phases. On the other hand, parameters, for example, high binder concentration in the liquid or large granule holdup, that favor drop deposition on granules and dust integration of wet particles reduce the drop and dust concentrations and thus the internal nucleation.
Kontinuierliche Wirbelschicht-Sprüh 造粒
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