Relationship between vision impairment and eye disease to vision-specific quality of life and function in rural India: The Aravind Comprehensive Eye Survey
Relationship between vision impairment and eye disease to vision-specific quality of life and function in rural India: The Aravind Comprehensive Eye Survey
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DOI：
10.1167/iovs.04-0830
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发表时间：
2005-07-01
影响因子：
4.4
通讯作者：
Robin, AL
中科院分区：
文献类型：
--
作者：
Nirmalan, PK;Tielsch, JM;Robin, AL
目的。目的：探讨印度南部农村老年人群视力障碍和眼病对视觉特异性生活质量和视觉功能的影响。通过从印度南部农村50个村庄的随机整群抽样策略，确定了40岁及以上人口的表现和最佳矫正视力以及眼病负担。一份先前在该人群中使用的问卷被用来确定生活质量和视觉功能。视力测量采用文盲E早期治疗糖尿病视网膜病变研究（ETDRS）图表。根据晶状体混浊分类系统（los） III对白内障进行分级和定义。黄斑变性的定义是基于国际ARM流行病学研究组提出的分类系统。青光眼的定义是根据临床检查的结果，包括视盘和视野。分析了总体和亚量表生活质量和视觉功能评分与视力较好的眼睛、特定眼病和人口统计学变量的表现敏锐度之间的关系。5150名研究对象中有5119名（99.4%）获得了生活质量和视觉功能的信息。正常眼的平均表现视力为0.76±0.53 logMAR（最小分辨角的对数）单位。年龄、教育程度、职业、表现较好眼的灵敏度、白内障、青光眼或屈光不正的存在与总体生活质量和视力功能评分独立相关。在调整了人口统计学变量和眼部疾病后，视力受损或双侧失明的人在生活质量和视力功能的所有领域得分都较低。年龄相关性白内障和青光眼患者的生活质量和视力功能域亚量表得分明显低于无这些眼病的患者。在印度南部农村的老年人口中，表现出较好的视力与生活质量和视力功能有关。青光眼和老年性白内障患者的生活质量和视觉功能均有相关下降，与较好眼的视力无关。
Purpose. To determine the impact of vision impairment and eye diseases on vision-specific quality of life and visual function in an older population of rural southern India.Methods. Presenting and best-corrected visual acuity and burden of eye diseases were determined in a population aged 40 years and older, identified through a random cluster sampling strategy from 50 villages of rural south India. A questionnaire validated previously for use in this population was used to ascertain quality of life and visual function. Visual acuity measurements were obtained with illiterate E Early Treatment Diabetic Retinopathy Study (ETDRS) charts. Cataract was graded and defined based on the Lens Opacities Classification System (LOCS) III. Macular degeneration was defined based on the classification system proposed by the International ARM Epidemiologic Study Group. Glaucoma was defined based on results of clinical examinations including optic disc and visual fields. Analyses were performed to explore the relationship of overall and subscale quality-of-life and visual function scores with presenting acuity in the better-seeing eye, specific eye diseases, and demographic variables.Results. Information on quality of life and visual function were available for 5119 (99.4%) of 5150 study subjects. The mean presenting visual acuity in the better eye was 0.76 +/- 0.53 logMAR (logarithm of the minimum angle of resolution) units. Age, education, occupation, presenting acuity in the better eye, and presence of a cataract, glaucoma, or refractive error were independently associated with overall quality-of-life and vision function scores. After adjustment for demographic variables and ocular disease, persons with vision impairment or bilateral blindness based on presenting visual acuity had lower scores across all domains of quality of life and vision function. Scores for subscales of quality-of-life and vision function domains were significantly lower among those with age-related cataract and glaucoma compared with persons without those eye diseases.Conclusions. Presenting vision in the better eye was associated with quality of life and vision function in this older population of rural south India. Subjects with glaucoma and age-related cataract had an associated decrease in quality of life and vision function, independent of presenting visual acuity in the better eye.