Repeated investigations of cyclophosphamide disposition in myeloma patients receiving intermittent chemotherapy.
Repeated investigations of cyclophosphamide disposition in myeloma patients receiving intermittent chemotherapy.
复制标题
接受间歇化疗的骨髓瘤患者环磷酰胺处置的重复调查。
DOI：
10.1111/j.1365-2125.1980.tb01756.x
复制
发表时间：
1980
影响因子：
3.4
通讯作者：
H. Scarffe
中科院分区：
文献类型：
--
作者：
G. Edwards;R. Calvert;D. Crowther;V. Bramwell;H. Scarffe
研究了一组骨髓瘤患者体内环磷酰胺的分布。在两次调查之间，环磷酰胺的清除率和分布量发生了显著变化。观察到的处置变化与肾脏和肝功能的生化评估或血浆蛋白状态无关。
1 The disposition of cyclophosphamide was investigated in a group of myeloma patients. 2 Marked changes in clearance and volume of distribution of cyclophosphamide occurred between investigations. 3 The observed changes in disposition did not correlate with biochemical estimates of renal and hepatic function or plasma protein status.