Static micromixers based on large-scale industrial mixer geometry
Static micromixers based on large-scale industrial mixer geometry
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DOI：
10.1039/b103848f
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发表时间：
2001-01-01
期刊：
影响因子：
6.1
通讯作者：
Renaud, P
中科院分区：
文献类型：
--
作者：
Bertsch, A;Heimgartner, S;Renaud, P
在微尺度下混合液体是困难的，因为微通道和微反应器中的低雷诺数禁止使用基于机械致动器的常规混合技术并引起湍流。静态混合器可以用来解决这个混合问题。本文介绍了微混合器的几何形状非常接近传统的大型静态混合器用于化学和食品加工工业。研究了两种几何形状。第一种类型由一系列固定的刚性元件组成，这些刚性元件形成交叉通道以分裂、重新排列和联合收割机组合分量流。第二种类型由成对布置的一系列短螺旋元件组成，每对包括在管道中交替布置的右旋元件和左旋元件。这两种类型的微混合器都是通过CAD设计的，并采用集成微立体光刻工艺制造，这是一种新的微制造技术，可以在聚合物中制造复杂的三维物体。实现的混频器已经过实验测试。使用计算流体动力学（CFD）程序FLUENT（TM）对这些微混合器进行数值模拟以评估混合效率。具有低压降和良好的混合效率，这些真正的三维微混合器可用于在许多mTAS应用中混合反应物或含有细胞的液体。
Mixing liquids at the micro-scale is difficult because the low Reynolds numbers in microchannels and in microreactors prohibit the use of conventional mixing techniques based on mechanical actuators and induce turbulence. Static mixers can be used to solve this mixing problem. This paper presents micromixers with geometries very close to conventional large-scale static mixers used in the chemical and food-processing industry. Two kinds of geometries have been studied. The first type is composed of a series of stationary rigid elements that form intersecting channels to split, rearrange and combine component streams. The second type is composed of a series of short helix elements arranged in pairs, each pair comprised of a right-handed and left-handed element arranged alternately in a pipe. Micromixers of both types have been designed by CAD and manufactured with the integral microstereolithography process, a new microfabrication technique that allows the manufacturing of complex three-dimensional objects in polymers. The realized mixers have been tested experimentally. Numerical simulations of these micromixers using the computational fluid dynamics (CFD) program FLUENT(TM) are used to evaluate the mixing efficiency. With a low pressure drop and good mixing efficiency these truly three-dimensional micromixers can be used for mixing of reactants or liquids containing cells in many m TAS applications.