Population-averaged standard template brain atlas for the common marmoset (Callithrix jacchus)
Population-averaged standard template brain atlas for the common marmoset (Callithrix jacchus)
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DOI：
10.1016/j.neuroimage.2010.10.061
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发表时间：
2011-02-14
期刊：
影响因子：
5.7
通讯作者：
Okano, H.
中科院分区：
文献类型：
--
作者：
Hikishima, K.;Quallo, M. M.;Okano, H.
基于体素统计的高级磁共振(MR)神经成像分析技术，如基于体素的形态测量(VBM)和功能MRI，被广泛应用于人类受试者和非人类灵长类动物的认知脑研究。成像技术的最新发展使得对具有足够空间分辨率的较小动物模型的评估成为可能。常见的绒猴(Callithrix Jacchus)是新大陆的一种小型灵长类物种，已被广泛应用于神经科学研究，体素统计可以通过特定物种的大脑模板扩展到这一领域。在这里，我们首次报道了常见绒猴大脑的组织分段、种群平均的标准模板。该模板是通过使用来自22只成年绒猴的解剖T-1加权图像创建的，其中7-特斯拉的高分辨率各向同性体素大小为0.2 mm(3)，SPM8中的Dartel算法。全脑模板可在国际神经信息学日本节点网站http://brainatlas.brainsikenjp/marmoset/.上获得(C)2010 Elsevier Inc.保留所有权利。
Advanced magnetic resonance (MR) neuroimaging analysis techniques based on voxel-wise statistics, such as voxel-based morphometry (VBM) and functional MRI, are widely applied to cognitive brain research in both human subjects and in non-human primates. Recent developments in imaging have enabled the evaluation of smaller animal models with sufficient spatial resolution. The common marmoset (Callithrix jacchus), a small New World primate species, has been widely used in neuroscience research, to which voxel-wise statistics could be extended with a species-specific brain template. Here, we report, for the first time, a tissue-segmented, population-averaged standard template of the common marmoset brain. This template was created by using anatomical T-1-weighted images from 22 adult marmosets with a high-resolution isotropic voxel size of (0.2 mm)(3) at 7-Tesla and DARTEL algorithm in SPM8. Whole brain templates are available at International Neuroinformatics Japan Node website, http://brainatlas.brainsikenjp/marmoset/. (C) 2010 Elsevier Inc. All rights reserved.