Citrate-capped Mn-modified CdSe/CdS quantum dots as luminescent probes for levodopa detection in aqueous solution
Citrate-capped Mn-modified CdSe/CdS quantum dots as luminescent probes for levodopa detection in aqueous solution
复制标题
柠檬酸封端的 Mn 修饰的 CdSe/CdS 量子点作为发光探针用于水溶液中左旋多巴的检测
DOI：
10.1016/j.saa.2012.01.081
复制
发表时间：
2012-06-01
影响因子：
4.4
通讯作者：
Hu, Qin
中科院分区：
文献类型：
--
作者：
Hu, Miao;Yu, Hailin;Hu, Qin
研制了一种柠檬酸盐封顶的mn修饰CdSe/CdS量子点。mn修饰的CdSe/CdS量子点发射窄且对称，荧光强，量子产率超过41%。研究了量子点与左旋多巴的相互作用。结果表明，左旋多巴选择性猝灭量子点的荧光强度。利用左旋多巴合成的量子点的荧光猝灭特性，提出了一种简单、快速、特异的左旋多巴定量方法。研究了影响左旋多巴荧光检测的因素。在最佳条件下，荧光猝灭强度与左旋多巴浓度在1 ~ 100 μ M范围内呈良好的线性关系，相关系数为0.9996，检出限（3 σ /K）为2 × 10(-7) M。(C) 2012 Elsevier B.V.版权所有
A novel kind of citrate capped Mn-modified CdSe/CdS quantum dots (QDs) was developed. The Mn-modified CdSe/CdS QDs had a narrow, symmetric emission and strong fluorescence with quantum yield over 41%. The interaction between the QDs and levodopa was investigated. The results showed that levodopa selectively quenched the fluorescence intensity of the QDs. Based on the fluorescence quenching of the synthesized QDs by levodopa, a simple, rapid and specific quantitative method for levodopa was proposed. The factors affecting the fluorescence detection for levodopa were studied. Under the optimum conditions, the quenched intensity of the fluorescence versus levodopa concentration from 1 to 100 mu M gave a linear response with an excellent correlation coefficient of 0.9996, and the limit of detection (3 sigma/K) was 2 x 10(-7) M. The contents of levodopa in pharmaceutical tablets were determined by the proposed method and the results agreed with the claimed values. (C) 2012 Elsevier B.V. All rights reserved.