Susceptibility of Ixodes persulcatus and I. ovatus (Acari: Ixodidae) to Lyme disease spirochetes isolated from humans in Japan.
Susceptibility of Ixodes persulcatus and I. ovatus (Acari: Ixodidae) to Lyme disease spirochetes isolated from humans in Japan.
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Ixodes persulcatus 和 I. ovatus（螨虫：Ixodidae）对从日本人类分离的莱姆病螺旋体的敏感性。
DOI：
10.1093/jmedent/31.3.467
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发表时间：
1994
影响因子：
2.1
通讯作者：
K. Miyamoto
中科院分区：
文献类型：
--
作者：
M. Nakao;K. Miyamoto
在实验室条件下，研究了全沟硬蜱和卵形硬蜱对莱姆病螺旋体的敏感性。从日本患者中分离的6株病毒(JEM3、JEM4、JEM5、JEM6、JEM7和JEM8)用于研究。将各分离株分别接种于蒙古沙鼠的腹膜内。全沟伊蚊和卵形伊蚊的幼虫被允许取食沙鼠，并被饲养以发育成若虫。在所有被检查的人类分离株中，这两个物种的饱满幼虫都摄取了螺旋体。然而，在蜕皮过程中，螺旋体感染的滞留仅在全硫隐翅虫中观察到。这些数据清楚地表明，全沟螺旋体对人类致病的螺旋体很敏感。在日本，莱姆病传播给人类的主要媒介被认为是全沟伊蚊。
Susceptibility of Ixodes persulcatus Schulze and Ixodes ovatus Neumann to Lyme disease spirochetes isolated from humans was studied under laboratory conditions. Six isolates (JEM3, JEM4, JEM5, JEM6, JEM7, and JEM8) from patients in Japan were used for the study. Mongolian jirds were inoculated intraperitoneally with each of the isolates. Larval ticks of either I. persulcatus or I. ovatus were allowed to feed on the jirds and reared for development into nymphs. In all human isolates examined, the replete larvae of both tick species ingested spirochetes. However, retention of the spirochetal infections through the molting process was observed only in I. persulcatus. These data clearly indicate that I. persulcatus is susceptible to the spirochetes that are pathogenic to humans. The principal vector of Lyme disease to humans in Japan is considered to be I. persulcatus.