LVIS Stent Versus Enterprise Stent for the Treatment of Unruptured Intracranial Aneurysms
LVIS Stent Versus Enterprise Stent for the Treatment of Unruptured Intracranial Aneurysms
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LVIS 支架与 Enterprise 支架治疗未破裂颅内动脉瘤的比较
DOI：
10.1016/j.wneu.2016.04.057
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发表时间：
2016-07-01
影响因子：
2
通讯作者：
Li, Youxiang
中科院分区：
文献类型：
--
作者：
Ge, Huijian;Lv, Xianli;Li, Youxiang
目的：材料与方法：2014年11月至2015年12月，对190例患者共208个未破裂颅内动脉瘤行LVIS和Enterprise支架辅助弹簧圈栓塞术。回顾性分析了手术相关并发症、临床结局和血管造影结果。结果：共92例患者的96个动脉瘤接受了LVIS支架治疗，98例患者的112个动脉瘤接受了Enterprise支架治疗。LVIS支架组中10.9%的患者发生了手术相关并发症（2起出血事件和8起血栓栓塞事件），而Enterprise支架组中16.3%的患者发生了手术相关并发症（1起出血事件、1起占位效应和14起血栓栓塞事件）。两组之间在血栓栓塞（P = 0.263）、出血并发症（P = 0.611）和有利的临床结局（改良兰金评分为0-2）（P = 0.379）方面无统计学显著差异。LVIS支架组的初始完全闭塞或接近完全闭塞率高于Enterprise支架组（96.9% vs. 88.4%，P = 0.034）。较大的动脉瘤尺寸（P = 0.048）是一个独立的预测程序相关的并发症在单变量analysis.CONCLUSIONS：与企业支架相比，LVIS支架可以实现更大的完全或接近完全闭塞率。LVIS和Enterprise支架之间的手术相关并发症和临床结局无显著差异。
OBJECTIVE: This retrospective study compared clinical and angiographic outcomes between LVIS and Enterprise stents.MATERIALS AND METHODS: From November 2014 to December 2015, total 190 patients with 208 unruptured intracranial aneurysms were coiled assisted by LVIS and Enterprise stents. Procedure-related complications, clinical outcomes, and angiographic results were analyzed retrospectively.RESULTS: A total of 92 patients with 96 aneurysms received LVIS stents and 98 patients with 112 aneurysms were treated with Enterprise stents. Procedure-related complications occurred in 10.9% of patients (2 hemorrhagic events and 8 thromboembolic events) in the LVIS stents group whereas 16.3% (1 hemorrhage, 1 mass effect, and 14 thromboembolic events) in the Enterprise stents group. No statistical significant differences in thromboembolic (P = 0.263), hemorrhagic complications (P = 0.611), and favorable clinical outcomes (modified Rankin Scores of 0-2) (P = 0.379) were found between 2 groups. A greater initial complete or near-complete obliteration was found in the LVIS stents group compared with the Enterprise stents group (96.9% vs. 88.4%, P = 0.034). Larger aneurysm size (P = 0.048) was an independent predictor of procedure-related complications in univariate analysis.CONCLUSIONS: Compared with Enterprise stents, LVIS stents may achieve greater complete or near-complete occlusion rate. There was no significant difference in procedural-related complications and clinical outcomes between LVIS and Enterprise stents.