Attenuated maximal muscle strength and peak power in children with sickle cell disease.
Attenuated maximal muscle strength and peak power in children with sickle cell disease.
复制标题
DOI：
10.1097/mph.0b013e318200ef49
复制
发表时间：
2011-03
期刊：
影响因子：
--
通讯作者：
Zemel BS
中科院分区：
文献类型：
--
作者：
Dougherty KA;Schall JI;Rovner AJ;Stallings VA;Zemel BS
在5- 13岁患有和不患有SS型镰状细胞病（SCD-SS）的非裔美国儿童中，比较了用握力计测量的优势手最大握力和用测力板测量的峰值功率，并根据体型和成分进行了调整。与健康对照组（n = 103，8.6 ± 1.8岁）相比，患有SCD-SS的儿童（n = 35，9.0 ± 2.0岁）在年龄、性别或青春期状态方面没有差异，但身高、体重、体重指数、上臂肌肉面积、上臂脂肪面积、脂肪和瘦体重身高比Z评分显著降低。SCD-SS儿童的握力显著低于正常儿童（12.7 ± 3.3 vs. 15.2 ± 5.1 kg，P < 0.008），峰值功率（882 ± 298 vs. 1167 ± 384 W，P < 0.001）和生长和身体成分调整的Z评分，用于握力（0.6 ± 1.3标准差，P < 0.004）和峰值功率（男性= 1.0 ± 0.8，P < 0.0002;女性= 1.0 ± 1.7，P < 0.006）。最大肌肉力量和峰值功率在儿童与SCD-SS相比，超出预期的增长和身体成分的赤字表明其他因素有助于衰减无氧性能的控制衰减。
Dominant hand maximal handgrip strength with a handgrip dynamometer and peak power with a force plate, adjusted for body size and composition were compared in 5- to 13-yr-old African-American children with and without type SS sickle cell disease (SCD-SS). Children with SCD-SS (n = 35, 9.0 ± 2.0 yrs) compared to healthy controls (n = 103, 8.6 ± 1.8 yrs) did not differ by age, gender, or pubertal status, yet had significantly lower Z scores for height, weight, body mass index, upper arm muscle area, upper arm fat area, fat and lean mass-for-height. Children with SCD-SS had significantly lower handgrip strength (12.7 ± 3.3 vs. 15.2 ± 5.1 kg, P < 0.008), peak power (882 ± 298 vs. 1167 ± 384 W, P < 0.001) and growth and body composition adjusted Z scores for handgrip strength (0.6 ± 1.3 standard deviations, P < 0.004) and peak power (males = 1.0 ± 0.8, P < 0.0002; females = 1.0 ± 1.7, P < 0.006). Maximal muscle strength and peak power are attenuated in children with SCD-SS compared to controls beyond expectation for growth and body composition deficits suggesting additional factors contribute to the attenuation in anaerobic performance.