Deafness - Cross-modal plasticity and cochlear implants
Deafness - Cross-modal plasticity and cochlear implants
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DOI：
10.1038/35051653
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发表时间：
2001-01-11
期刊：
影响因子：
64.8
通讯作者：
Kim, CS
中科院分区：
文献类型：
--
作者：
Lee, DS;Lee, JS;Kim, CS
通过在内耳植入一个植入物来刺激耳蜗神经，可以帮助深度聋人的听力。这也促进了听觉皮质的低代谢活动，这是大脑中通常用于听力的区域。其他感觉形式，如手语，也可以激活听觉皮质，这一现象被称为跨模式可塑性。在这里，我们展示了当语言前期失聪儿童(他们在学会说话之前就失去了听力)的新陈代谢通过跨模式可塑性恢复后，听觉皮质不再能对后来安装的人工耳蜗的信号做出反应。因此，在语言前期失聪患者中，听觉皮质中的神经底物可能永久地被路由到其他认知过程。
Hearing in profoundly deaf people can be helped by inserting an implant into the inner ear to stimulate the cochlear nerve. This also boosts the low metabolic activity of the auditory cortex, the region of the brain normally used for hearing. Other sensory modalities, such as sign language, can also activate the auditory cortex, a phenomenon known as cross-modal plasticity. Here we show that when metabolism in the auditory cortex of prelingually deaf children (whose hearing was lost before they learned to talk) has been restored by cross-modal plasticity, the auditory cortex can no longer respond to signals from a cochlear implant installed afterwards. Neural substrates in the auditory cortex might therefore be routed permanently to other cognitive processes in prelingually deaf patients.