Carotid Intima-Media Thickness and Coronary Artery Calcium Score as Indications of Subclinical Atherosclerosis
Carotid Intima-Media Thickness and Coronary Artery Calcium Score as Indications of Subclinical Atherosclerosis
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DOI：
10.4065/84.3.229
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发表时间：
2009-03-01
影响因子：
8.9
通讯作者：
Hurst, R. Todd
中科院分区：
文献类型：
--
作者：
Lester, Steven J.;Eleid, Mackram F.;Hurst, R. Todd
目的：探讨颈动脉内膜-中膜厚度（CIMT）和冠状动脉钙化评分（CACS）在中青年、低危、初级预防人群中检测亚临床动脉粥样硬化的能力。患者和方法：2004年5月1日至2008年4月1日期间在我院接受CIMT和CACS检测的36 - 59岁患者纳入研究。排除有糖尿病或有冠状动脉、外周血管或脑血管病史者。其他信息，如Framingham风险评分（FRS），是通过对临床和实验室数据的回顾获得的。结果：118例患者中，89例（75%）CACS为零，94例（80%）为男性；平均±SD年龄为48.9±5.7岁。本组平均FRS为4.0；86例（97%）为低危(
OBJECTIVE: To determine the ability of carotid Intima-media thickness (CIMT) and coronary artery calcium score (CACS) to detect subclinical atherosclerosis In a young to middle-aged, low-risk, primary-prevention population.PATIENTS AND METHODS: Patients aged 36 to 59 years who underwent determination of CIMT and CACS at our Institution between May 1, 2004, and April 1, 2008, were Included In the study. Those with diabetes mellitus or a history of coronary, peripheral, or cerebral vascular disease were excluded. Other Information, such as Framingham risk score (FRS), was obtained by a review of clinical and laboratory data.RESULTS: Of 118 patients, 89 (75%) had a CACS of zero and 94 (80%) were men; mean +/- SD age was 48.9 +/- 5.7 years. The mean FRS of this group was 4.0; 86 patients (97%) were considered at low risk (