High-Order Cardiomyopathy Human Heart Model and Mesh Generation.
High-Order Cardiomyopathy Human Heart Model and Mesh Generation.
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高阶心肌病人体心脏模型及网格生成。
DOI：
10.23919/cinc53138.2021.9662923
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发表时间：
2021-09
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忠实、准确和成功的心脏生物力学和电生理模拟需要患者特定的心脏几何模型。由于心脏几何结构由高度弯曲的边界组成，因此使用具有弯曲元素的高阶网格将确保心脏几何结构中存在的各种曲线和特征被很好地捕获并保留在相应的网格中。大多数其他现有的网格生成技术需要计算机辅助设计文件来表示几何边界，这通常不适用于生物医学应用。与这样的方法不同，我们的技术需要一个高阶表面网格，从患者的医学图像，作为输入，并直接从曲面网格生成一个高阶体积网格。在本文中，我们使用我们的直接高阶曲线四面体网格生成方法来生成几个二阶心脏网格。我们的网格包括健康心脏和扩张型和肥厚型心肌病心脏的左心室心肌。我们表明，我们的高阶心脏网格不包含倒置的元素，并在心脏有限元模拟中使用足够高的质量。
Faithful, accurate, and successful cardiac biomechanics and electrophysiological simulations require patient-specific geometric models of the heart. Since the cardiac geometry consists of highly-curved boundaries, the use of high-order meshes with curved elements would ensure that the various curves and features present in the cardiac geometry are well-captured and preserved in the corresponding mesh. Most other existing mesh generation techniques require computer-aided design files to represent the geometric boundary, which are often not available for biomedical applications. Unlike such methods, our technique takes a high-order surface mesh, generated from patient medical images, as input and generates a high-order volume mesh directly from the curved surface mesh. In this paper, we use our direct high-order curvilinear tetrahedral mesh generation method to generate several second-order cardiac meshes. Our meshes include the left ventricle myocardia of a healthy heart and hearts with dilated and hypertrophic cardiomyopathy. We show that our high-order cardiac meshes do not contain inverted elements and are of sufficiently high quality for use in cardiac finite element simulations.