N1m recovery from decline after exposure to noise with strong spectral contrasts

N1m recovery from decline after exposure to noise with strong spectral contrasts
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DOI:
10.1016/j.heares.2004.04.017
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发表时间:
2004-10-01
期刊:
影响因子:
2.8
通讯作者:
Pantev, C
Pantev, C
中科院分区:
医学1区
文献类型:
--
作者:
Okamoto, H;Ross, B;Pantev, C

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梳状滤波噪声(CFN,通过抑制规则间隔的频率区域从白色噪声得到)呈现3秒,随后是两种类型的测试刺激。一个测试刺激(SB)由以CFN的阻带区域为中心的光谱组成,另一个测试刺激(PB)由以CFN的带通区域为中心的光谱组成。脑磁图记录的SB刺激诱发的N1m反应相对于PB刺激诱发的N1m反应降低。当CFN和测试刺激之间的间隔很短(0.5秒)时,这种效果是最大的,但在最多2秒的间隔检测到。结果表明,听觉皮层存在侧抑制,并指出抑制的衰减持续了几秒钟。(C)2004 Elsevier B.V.保留所有权利。
Comb-filtered noise (CFN, derived from white noise by suppressing regularly spaced frequency regions) was presented for 3 s followed by two types of test stimuli. One test stimulus (SB) was comprised of spectra centered in the stop-band regions of the CFN and the other test stimulus (PB) of spectra centered in the band pass regions of the CFN. Magnetoencephalographically recorded N1m responses evoked by SB stimuli were decreased relative to the N1m response evoked by PB stimuli. This effect was maximal when the interval between the CFN and test stimuli was short (0.5 s) but was detected at intervals up to 2 s. The results suggest lateral inhibition in the auditory cortex and point to a decay of inhibition lasting on the order of seconds. (C) 2004 Elsevier B.V. All rights reserved.