The effects of restricted food access upon locomotor activity in rats with suprachiasmatic nucleus lesions
The effects of restricted food access upon locomotor activity in rats with suprachiasmatic nucleus lesions
复制标题
限制食物获取对视交叉上核病变大鼠运动活动的影响
DOI：
10.1016/0031-9384(79)90364-0
复制
发表时间：
1979
影响因子：
2.9
通讯作者：
P. Mikulka
中科院分区：
文献类型：
--
作者：
Jerry L. M. Phillips;P. Mikulka
本研究的目的是研究视交叉上核（SCN）损伤大鼠对限制性食物获取（RFA）的预测能力。假手术对照组的运动活动表现出LD 12:12循环的运动活动，并提供自由的食物和水，而受损动物的跑步行为则是不规律的。当暴露于恒定光（LL）和每24小时提供一次食物时，两组都观察到预期轮运行。回到即食食物和之前的LD 12:12时间表，在对照组和SCN动物中产生了缓慢的跑步和不规律的活动。结果表明，SCN对大鼠运动节律的出现并不是必需的。
The purpose of the study was to investigate the ability of rats with suprachiasmatic nucleus (SCN) lesions to anticipate restricted food access (RFA). The sham operated controls demonstrated entrainment of locomotor activity to a LD 12:12 cycle with ad libitum food and water, while the lesioned animals were arrhythmic in their running behavior. When exposed to constant light (LL) and presentation of food once every 24 hours, anticipatory wheel running was observed in both groups. A return to ad lib food and the previous LD 12:12 schedule produced a slow re-entrainment of running in the controls and arrhythmic activity in the SCN animals. The results suggest that the SCN is not necessary for the appearance of locomotor rhythms in the rat.