Transcatheter Arterial Embolization Using Imipenem/Cilastatin Sodium for Tendinopathy and Enthesopathy Refractory to Nonsurgical Management
Transcatheter Arterial Embolization Using Imipenem/Cilastatin Sodium for Tendinopathy and Enthesopathy Refractory to Nonsurgical Management
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DOI：
10.1016/j.jvir.2013.02.033
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发表时间：
2013-06-01
影响因子：
2.9
通讯作者：
Oguro, Sota
中科院分区：
文献类型：
--
作者：
Okuno, Yuji;Matsumura, Noboru;Oguro, Sota
目的：评估亚胺培南/西司他丁钠 (CS) 经导管动脉栓塞治疗传统非手术治疗难治性肌腱病和附着点病的可行性和效果。 材料和方法：对 7 名肌腱病和附着点病患者（5 名男性；肉龄，51.7 岁）进行亚胺培南/西司他丁钠作为栓塞剂的经导管动脉栓塞术（髌腱病，n = 1；肩袖肌腱病，n = 2；足底筋膜炎，n = 1；外上髁炎，n = 1；髂胫束综合征，n = 1；跟腱附着肌腱病，n = 1）。所有患者在手术前都有肌腱病和附着点病部位的持续疼痛。对技术成功、不良事件和视觉模拟量表 (VAS) 评分的变化进行了评估。结果：所有手术在技术上都是成功的，并且没有发生重大不良事件。与手术前相比，平均VAS评分为。术后 1 天、1 周、1 个月和 4 个月显着下降（分别为 72.7 mm +/- 9.0 与 17.4 +/- mm +/- 18.5、16.0 mm +/- 18.1、13.7 mm +/- 7.3 和 9.7 mm +/- 6.8；所有 P < .001）。结论：经导管动脉栓塞亚胺培南/CS 是可行的，可以有效缓解与肌腱病和附着点病相关的持续疼痛。
Purpose: To evaluate the feasibility and effects of transcatheter arterial embolizatiori with imipenem/cilastatin sodium (CS) to treat tendinopathy and enthesopathy that are refractory to traditional nonsurgical management.Materials and Methods: Transcatheter arterial embolization with imipenem/CS as an embolic agent was performed in seven patients (five men; meat age, 51.7 y) with tendinopathy and enthesopathy (patellar tendinopathy, n = 1; rotator cuff tendinopathy, n = 2; plantar fasciitis, n = 1; lateral epicondylitis, n = 1; iliotibial band syndrome, n = 1; and, Achilles insertion tendinopathy, n = 1). All patients had unrelenting pain at the site of tendinopathy and enthesopathy before the procedure. Technical success, adverse events, and changes in visual analog scale (VAS) scores Were assessed.Results: All procedures were technically successful, and no major adverse events developed. Compared with before the procedure, mean VAS scores were. significantly decreased at 1 day, 1 week, and 1 and 4 months After the procedure (72.7 mm +/- 9.0 vs 17.4 +/- mm +/- 18.5, 16.0 mm +/- 18.1, 13.7 mm +/- 7.3, and 9.7 mm +/- 6.8, respectively; all P < .001).Conclusions: Transcatheter arterial embolization with imipenem/CS was feasible and effectively relieved unrelenting pain associated with tendinopathy and enthesopathy.