Fly Photoreceptors Encode Phase Congruency.
Fly Photoreceptors Encode Phase Congruency.
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DOI：
10.1371/journal.pone.0157993
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发表时间：
2016
期刊：
影响因子：
3.7
通讯作者：
Coca D
中科院分区：
文献类型：
--
作者：
Friederich U;Billings SA;Hardie RC;Juusola M;Coca D
五十多年前，人们假设感觉神经元检测并选择性地增强自然信号的行为相关特征。尽管我们现在知道感觉神经元可以有效地编码自然刺激，但到目前为止，我们还不清楚它们编码的刺激的统计特征是什么，以及它们是如何编码的。在这里，我们对果蝇光感受器的神经编码进行了逆向工程，并首次证明了光感受器利用非线性动力学来选择性地增强和编码时间刺激的相位相关特征，例如局部相位一致性，这些特征不随光照和对比度的变化而变化。我们证明，为了缓解局部相位一致性度量固有的对噪声的敏感性，苍蝇光感受器的非线性编码机制被调节以抑制随机相位信号，这解释了为什么光感受器对自然刺激的反应与对白噪声刺激的反应显著不同。
More than five decades ago it was postulated that sensory neurons detect and selectively enhance behaviourally relevant features of natural signals. Although we now know that sensory neurons are tuned to efficiently encode natural stimuli, until now it was not clear what statistical features of the stimuli they encode and how. Here we reverse-engineer the neural code of Drosophila photoreceptors and show for the first time that photoreceptors exploit nonlinear dynamics to selectively enhance and encode phase-related features of temporal stimuli, such as local phase congruency, which are invariant to changes in illumination and contrast. We demonstrate that to mitigate for the inherent sensitivity to noise of the local phase congruency measure, the nonlinear coding mechanisms of the fly photoreceptors are tuned to suppress random phase signals, which explains why photoreceptor responses to naturalistic stimuli are significantly different from their responses to white noise stimuli.