Original Research Put Into Perspective for the Practicing Clinician Incidence, Cause, and Comparative Frequency of Sudden Cardiac Death in National Collegiate Athletic Association Athletes: A Decade in Review

Original Research Put Into Perspective for the Practicing Clinician Incidence, Cause, and Comparative Frequency of Sudden Cardiac Death in National Collegiate Athletic Association Athletes: A Decade in Review
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2015
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年轻人心源性猝死(SCD)的发生率一直备受争议。在其他死亡风险的背景下准确了解总体发病率,以确定应考虑额外预防策略的人群,这一点很重要。这项研究证实了早期的研究结果,即全国大学生体育协会运动员(1/53703)的SCD发生率较高,男性(1/37790),黑人(1/21491)和男性篮球运动员(1/9000)的风险较高。事实上,一级联赛的男子篮球运动员死于SCD的可能性是死于车祸的5倍。这项研究还表明,在方法上的差异,以确定案件将极大地影响结果,媒体报道是一个不可靠的方式来确定SCD,特别是在低知名度的运动员。同样,使用保险索赔进行病例识别时,仅在运动员中检测到一小部分SCD(1/10)。这给准确了解高中和青年运动员SCD的发病率带来了挑战,没有更好的报告机制。这项研究发现,尸检阴性的不明原因的猝死比例(25%)比以前描述的美国运动员更高,肥厚性心肌病的比例(8%)更低。需要标准化的尸检和死后基因检测来更好地确定SCD的病因。国家大学体育协会的运动员目前在大学入学时接受心血管疾病的筛查。人们对资源使用表示关切,但在高危人群中可能需要进行更密集的筛查。参见第10页。
The incidence of sudden cardiac death (SCD) in young people is hotly debated. It is important to have an accurate understanding of the overall incidence in the context of other risks of death to identify groups where additional preventive strategies should be considered. This study confirms earlier findings of a higher rate of SCD in National Collegiate Athletic Association athletes (1 in 53 703) with males (1 in 37 790), blacks (1 in 21 491), and male basketball athletes (1 in 9000) at higher risk. In fact, Division I male basketball players are 5 times more likely to die of SCD than to die in a car accident. This study also demonstrates that the differences in methodology to identify cases will drastically affect results and that media reports are an unreliable way to identify SCD, in particular, in lower-profile athletes. Similarly, the use of insurance claims for case identification detected only a fraction of SCDs in athletes (1/10). This creates challenges to accurately understand the incidence of SCD in high school and youth athletes without better reporting mechanisms. This study found a higher proportion of autopsy-negative sudden unexplained death (25%) than previously described in US athletes and a lower proportion of hypertrophic cardiomyopathy (8%). Standardized autopsies and postmortem genetic testing are needed to better define the causes of SCD. National Collegiate Athletic Association athletes are currently screened at matriculation for cardiovascular disease. Concern has been expressed regarding resource use, but more intensive screening may be warranted in high-risk groups. See p 10.