APATHY FOLLOWING CEREBROVASCULAR LESIONS
APATHY FOLLOWING CEREBROVASCULAR LESIONS
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DOI：
10.1161/01.str.24.11.1625
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发表时间：
1993-11-01
期刊：
影响因子：
8.3
通讯作者：
ROBINSON, RG
中科院分区：
文献类型：
--
作者：
STARKSTEIN, SE;FEDOROFF, JP;ROBINSON, RG
背景和目的：虽然冷漠已被报道构成中风损害的常见后遗症，但尚未有关于中风损害后冷漠的频率和相关性的前瞻性研究。在本研究中，我们研究了80例脑血管病变患者的连续系列冷漠的频率和相关性。方法：我们纳入了中风后10天内的患者。患者进行了全面的神经精神电池，其中包括冷漠Scale.Results：18例（22.5%）表现出冷漠，其中9人也抑郁症。另一方面，18名患者（22.5%）在没有冷漠的情况下表现出抑郁。虽然抑郁和冷漠可能彼此独立存在，但重度抑郁（而不是轻度抑郁）与冷漠频率增加有关。冷漠还与年龄较大、认知障碍和日常生活活动缺陷显著相关。最后，冷漠与后肢的内囊病变显着相关。结论：这些研究结果表明，冷漠是一种常见的发现急性脑卒中病变患者，并可能与重要的情绪和认知卒中后障碍共存。
Background and Purpose: Although apathy has been reported to constitute a frequent sequela of stroke lesions, there have been no prospective studies on the frequency and correlates of apathy after stroke lesions. In the present study, we examined the frequency and correlates of apathy in a consecutive series of 80 patients with cerebrovascular lesions.Methods: We included patients within the first 10 days after a stroke lesion. Patients were examined with a comprehensive neuropsychiatric battery that included the Apathy Scale.Results: Eighteen patients (22.5%) showed apathy, nine of whom were also depressed. On the other hand, 18 patients (22.5%) showed depression in the absence of apathy. Although depression and apathy may exist independent of one another, major depression (but not minor depression) was associated with an increased frequency of apathy. Apathy was also significantly associated with older age, cognitive impairments, and deficits in activities of daily living. Finally, apathy was significantly associated with lesions in the posterior limb of the internal capsule.Conclusions: These findings demonstrate that apathy is a frequent finding among patients with acute stroke lesions and may coexist with important emotional and cognitive poststroke disturbances.