Immunotherapy for Head and Neck Squamous Cell Carcinoma.
Immunotherapy for Head and Neck Squamous Cell Carcinoma.
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DOI：
10.1007/s40496-016-0082-2
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发表时间：
2016-06
影响因子：
--
通讯作者：
Moyer JS
中科院分区：
文献类型：
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作者：
Hoesli RC;Moyer JS
头颈部鳞状细胞癌已被发现是一种免疫抑制的恶性肿瘤，宿主免疫系统的许多缺陷有助于疾病的进展。对这些缺陷的更深入了解导致了新的治疗策略的识别和研究，针对免疫系统功能障碍，努力改善这种疾病的结果。本文简要介绍了有关头颈癌免疫缺陷的知识，以及目前正在研究使用的治疗策略。
Head and neck squamous cell carcinoma has been found to be an immunosuppressive malignancy, with many defects in the host immune system contributing to the progression of disease. A greater understanding of these defects has lead to the identification and investigation of new therapeutic strategies, targeting immune system dysfunction in an effort to improve the outcomes of this disease. This article provides a brief review of the knowledge regarding the immune defects present in head and neck cancer, as well as a review of the current therapeutic strategies being investigated for use.